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Dexrazoxane

Known as: 2, 6-Piperazinedione, 4,4'-propylenedi-, (P)- (8CI), Dexrazoxanum, Dexrazoxano 
The active ingredient in a drug used to treat severe side effects caused by certain anticancer drugs. Under the brand name Totect it is used to treat… 
National Institutes of Health

Papers overview

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Highly Cited
2007
Highly Cited
2007
Doxorubicin is among the most effective and widely used anticancer drugs in the clinic. However, cardiotoxicity is one of the… 
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Highly Cited
2007
Highly Cited
2007
PURPOSE Pediatric Oncology Group (POG) studies 9426 and 9425 evaluated dexrazoxane (DRZ) as a cardiopulmonary protectant during… 
Highly Cited
2004
Highly Cited
2004
BACKGROUND Doxorubicin chemotherapy is very effective in children with acute lymphoblastic leukemia (ALL) but also injures… 
Highly Cited
2004
Highly Cited
2004
This paper presents the first comprehensive major and trace element data for � 130 abyssal peridotite samples from the Pacific… 
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Highly Cited
2000
Highly Cited
2000
Fractionation of some or all of the high field strength elements (HFSE) Nb, Ta, Zr, Hf, and Ti relative to other trace elements… 
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Highly Cited
1997
Highly Cited
1997
The International Mineralogical Association's approved amphibole nomenclature has been revised to simplify it, make it more… 
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Highly Cited
1997
Highly Cited
1997
PURPOSE To determine the cardioprotective effect of dexrazoxane (DZR) used in a doxorubicin-based combination therapy in advanced… 
Review
1992
Review
1992
  • R. Weiss
  • Seminars in oncology
  • 1992
  • Corpus ID: 46289384
The anthracyclines are the class of antitumor drugs with the widest spectrum of activity in human cancers, and only a few cancers…