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ICRF-187

Known as: ICRF 187, ICRF187 
 
National Institutes of Health

Papers overview

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Review
2013
Review
2013
SIGNIFICANCE Anthracyclines (doxorubicin, daunorubicin, or epirubicin) rank among the most effective anticancer drugs, but their… Expand
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Highly Cited
2012
Highly Cited
2012
Angelman syndrome is a severe neurodevelopmental disorder caused by deletion or mutation of the maternal allele of the ubiquitin… Expand
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Highly Cited
2007
Highly Cited
2007
Doxorubicin is among the most effective and widely used anticancer drugs in the clinic. However, cardiotoxicity is one of the… Expand
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Highly Cited
2007
Highly Cited
2007
The clinically approved antioxidant cardioprotective agent dexrazoxane (ICRF-187) was examined for its ability to protect… Expand
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Highly Cited
2003
Highly Cited
2003
Type IIA topoisomerases both manage the topological state of chromosomal DNA and are the targets of a variety of clinical agents… Expand
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Review
2000
Review
2000
Anthracycline antibiotics are among the most effective and widely used antineoplastic drugs. Their usefulness is limited by a… Expand
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Highly Cited
1996
Highly Cited
1996
PURPOSE We conducted an open-label, randomized trial to determine whether ICRF-187 would reduce doxorubicin-induced… Expand
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Highly Cited
1992
Highly Cited
1992
In this study doxorubicin, epirubicin, and mitoxantrone were compared for their cardiotoxic potential in a chronic mouse model in… Expand
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Highly Cited
1992
Highly Cited
1992
PURPOSE To test potential protection by ICRF-187 against cumulative doxorubicin-dose-related cardiac toxicity, we conducted a… Expand
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Highly Cited
1988
Highly Cited
1988
Studies in animals suggest that the bispiperazinedione ICRF-187 can prevent the development of dose-related doxorubicin-induced… Expand
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