ICRF-187

Known as: ICRF 187, ICRF187 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1980-2017
05101519802017

Papers overview

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Highly Cited
2003
Highly Cited
2003
Type IIA topoisomerases both manage the topological state of chromosomal DNA and are the targets of a variety of clinical agents… (More)
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1996
1996
PURPOSE We conducted an open-label, randomized trial to determine whether ICRF-187 would reduce doxorubicin-induced… (More)
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1996
1996
The occurrence of apoptosis in heart, kidney and small intestine was investigated in spontaneously hypertensive rats (SHR… (More)
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1995
1995
A series of twelve structurally related bisdioxopiperazines that included ICRF-187 (dexrazoxane), ICRF-159 (razoxane), ICRF-193… (More)
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Highly Cited
1992
Highly Cited
1992
PURPOSE To test potential protection by ICRF-187 against cumulative doxorubicin-dose-related cardiac toxicity, we conducted a… (More)
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1992
1992
In this study doxorubicin, epirubicin, and mitoxantrone were compared for their cardiotoxic potential in a chronic mouse model in… (More)
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1992
1992
BACKGROUND Although doxorubicin is an anticancer agent with a wide spectrum of activity, therapy with this anthracycline must… (More)
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Highly Cited
1988
Highly Cited
1988
Studies in animals suggest that the bispiperazinedione ICRF-187 can prevent the development of dose-related doxorubicin-induced… (More)
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1981
1981
To determine whether ICRF-187 (NSC-169780) would alter chronic daunorubicin (NSC-82151) cardiac toxicity, male New Zealand… (More)
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1981
1981
Adult beagle dogs were given doxorubicin (1.0 mg/kg body weight i.v.) either alone or 30 min after ICRF-187 (NSC 169780) (12.5 mg… (More)
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