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Antineoplastic Agents

Known as: Drugs, Cancer Chemotherapy, Cancer Drug, Antitumor Drugs 
A substance that inhibits the maturation, growth or spread of tumor cells.
National Institutes of Health

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1,9-dimethylmethylene blue1-arabinofuranosylcytosine-5'-stearylphosphate4-S-cysteaminylphenolAldesleukin
Chemotherapy, Cancer, Regional Perfusion

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
Modulation of intracellular ceramide using polymeric nanoparticles to overcome multidrug resistance in cancer.
Although multidrug resistance (MDR) is known to develop through a variety of molecular mechanisms within the tumor cell, many… 
Highly Cited
2002
Highly Cited
2002
Synthesis of 3-alkyl(aryl)-4-alkylidenamino-4,5-dihydro-1H-1,2,4-triazol-5-ones and 3-alkyl-4-alkylamino-4,5-dihydro-1H-1,2,4-triazol-5-ones as antitumor agents.
Highly Cited
1990
Highly Cited
1990
Decreased expression of DNA topoisomerase I in camptothecin-resistant tumor cell lines as determined by a monoclonal antibody.
DNA topoisomerase I (topo I) has been identified as a principal target of a plant alkaloid camptothecin (CPT) and its derivative… 
Highly Cited
1990
Highly Cited
1990
An early phase II study of CPT-11: a new derivative of camptothecin, for the treatment of leukemia and lymphoma.
An early phase II study of a new camptothecin analog and an inhibitor of topoisomerase I, CPT-11, was conducted in 62 patients… 
Highly Cited
1990
Highly Cited
1990
Total Synthesis of the Macrolide Antibiotic Cytovaricin.
A convergent asymmetric synthesis of the antinoeplastic macrolide antibiotic cytovaricin has been achieved through the synthesis… 
Highly Cited
1989
Highly Cited
1989
A new methodology for the optimal design and production schedule of multipurpose batch plants
Presentation d'une procedure algorithmique determinant simultanement le programme optimal de production et les tailles des… 
Highly Cited
1981
Highly Cited
1981
Association between human tumor colony-forming assay results and response of an individual patient's tumor to chemotherapy.
Highly Cited
1977
Highly Cited
1977
The Nephrotoxicity of Antimicrobial Agents
Selection of an antibiotic to use in the treatment of an infection should be based on benefittoxicity ratios, particularly in… 
Highly Cited
1976
Highly Cited
1976
Binding of platinum and palladium metallointercalation reagents and antitumor drugs to closed and open DNAs.
The interaction of platinum and palladium complexes with closed and nicked circular and linear DNAs was investigated by a variety… 
Highly Cited
1976
Highly Cited
1976
Distribution and disposition of platinum following intravenous administration of cis-diamminedichloroplatinum(II) (NSC 119875) to dogs.
cis-Diamminedichloroplatinum(II) is an antineoplastic drug that is undergoing a renewed clinical interest as a drug for use in… 
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