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4-S-cysteaminylphenol
Known as:
Phenol, 4-((2-aminoethyl)thio)-, (SP-4-1)-
National Institutes of Health
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Related topics
Related topics
3 relations
Broader (2)
Antineoplastic Agents
Cysteamine
analogs & derivatives
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2006
2006
Synthesis and antimelanoma activity of reversed amide analogues of N-acetyl-4-S-cysteaminylphenol.
K. Nicoll
,
J. Robertson
,
N. Lant
,
L. Kelland
,
P. Rogers
,
D. Robins
Oncology Research
2006
Corpus ID: 39924642
The melanin biosynthetic pathway from tyrosine is a potential target for combating malignant melanoma. N-Acetyl-4-S…
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2003
2003
Synthesis and antimelanoma activity of tertiary amide analogues of N-acetyl-4-S-cysteaminylphenol.
Vikki C Pearson
,
J. Ferguson
,
P. Rogers
,
L. Kelland
,
D. Robins
Oncology Research
2003
Corpus ID: 11102297
The biosynthetic pathway to melanin is a realistic target for therapeutic intervention in the development of new drugs to combat…
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2001
2001
Synthesis and anti-melanoma activity of analogues of N-acetyl-4-S-cysteaminylphenol substituted with two methyl groups alpha to the nitrogen.
Neil J. Lant
,
Paul Mckeown
,
Maire C. Timoney
,
Lloyd R. Kelland
,
Paul Rogers
,
David J. Robins
Anti-Cancer Drug Design
2001
Corpus ID: 42170955
N-Acetyl-4-S-cysteaminylphenol 1 is an analogue of a biosynthetic intermediate in the pathway to melanin. It is probably oxidized…
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2000
2000
Synthesis and antimelanoma activity of analogues of N-acetyl-4-S-cysteaminylphenol.
N. Lant
,
P. Mckeown
,
L. Kelland
,
P. Rogers
,
D. Robins
Anti-Cancer Drug Design
2000
Corpus ID: 34816732
N-Acetyl-4-S-cysteaminylphenol (1) has been shown by Jimbow and co-workers to possess useful antimelanoma activity. It is an…
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1998
1998
Synthesis and antitumour effect of the melanogenesis-based antimelanoma agent N-propionyl-4-S-cysteaminylphenol.
M. Tandon
,
P. Thomas
,
+4 authors
K. Jimbow
Biochemical Pharmacology
1998
Corpus ID: 24893726
1995
1995
Glutathione plays a key role in the depigmenting and melanocytotoxic action of N-acetyl-4-S-cysteaminylphenol in black and yellow hair follicles.
F. Alena
,
W. Dixon
,
P. Thomas
,
K. Jimbow
Journal of Investigative Dermatology
1995
Corpus ID: 40535632
This study examined the effect of glutathione on the in vivo depigmenting potency of N-acetyl-4-S-cysteaminylphenol (N-acetyl-4-S…
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1994
1994
The synthesis of N-acetyl-4-S-cysteaminyl [U-14C]phenol as a basis for the development of an antimelanoma and melanoma-radioimaging agent.
T. Iwashina
,
K. Jimbow
,
L. Wiebe
Applied Radiation and Isotopes
1994
Corpus ID: 23166440
1992
1992
Effects of tyrosinase activity on the cytotoxicity of 4-S-cysteaminylphenol and N-acetyl-4-S-cysteaminylphenol in melanoma cells.
J. Prezioso
,
M. Epperly
,
N. Wang
,
W. Bloomer
Cancer Letters
1992
Corpus ID: 24106953
Highly Cited
1991
Highly Cited
1991
N-acetyl-4-S-cysteaminylphenol as a new type of depigmenting agent for the melanoderma of patients with melasma.
K. Jimbow
Archives of Dermatology
1991
Corpus ID: 36138186
BACKGROUND AND DESIGN --Melasma is a difficult medical problem to treat. Hydroquinone is administered to many patients, but it is…
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