• Publications
  • Influence
Induction of Suppressor of Cytokine Signaling-3 by Herpes Simplex Virus Type 1 Contributes to Inhibition of the Interferon Signaling Pathway
TLDR
The SOCS3 protein appears to be mainly responsible for the suppression of IFN signaling and IFN production that occurs during HSV-1 infection. Expand
Mechanism of depigmentation by hydroquinone.
TLDR
Findings indicate that HQ affects not only the formation, melanization, and degradation of melanosomes, but that it affects also the membraneous structures of melanocytes and eventually causes necrosis of whole melanocytes. Expand
Congenital circumscribed hypomelanosis: a characterization based on electron microscopic study of tuberous sclerosis, nevus depigmentosus, and piebaldism.
TLDR
Subcellular defects of hypomelanosis in tuberous sclerosis (TS) and nevus depigmentosus (ND) were compared by light and electron microscopy with forms of congenital circumscribed hypomELanosis that occur in piebaldism (PB) and inPiebaldistan (PB), respectively. Expand
DUAL ROLE OF MELANINS AND MELANIN PRECURSORS AS PHOTOPROTECTIVE AND PHOTOTOXIC AGENTS: INHIBITION OF ULTRAVIOLET RADIATION‐INDUCED LIPID PEROXIDATION
TLDR
It is suggested that melanin precursors may have an important role in the protection of skin against the harmful effects of UVR including photocarcinogenesis. Expand
Herpes simplex virus type 1 suppresses the interferon signaling pathway by inhibiting phosphorylation of STATs and janus kinases during an early infection stage.
TLDR
Results indicate that viral gene expression or viral protein production is necessary for the inhibition of phosphorylation by HSV-1. Expand
4‐S‐Cysteaminylphenol‐loaded magnetite cationic liposomes for combination therapy of hyperthermia with chemotherapy against malignant melanoma
TLDR
The results suggest that this novel therapeutic tool, combining melanoma‐specific chemotherapy by 4‐S‐CAP with intracellular hyperthermia mediated by MCL, is applicable to the treatment of malignant melanoma. Expand
Increased sensitivity of melanocytes to oxidative stress and abnormal expression of tyrosinase‐related protein in vitiligo
TLDR
Tyrosinase‐related protein (TRP) 1 has been shown to be involved not only in melanin biosynthesis but also in the prevention of premature melanocyte death in animals. Expand
Pigmentary disorders in oriental skin.
Brown hyperpigmented disorders may be melanotic in which there is a normal number of epidermal melanocytes but melanin pigment is increased in the epidermis (eg, melasma), melanocytotic, in whichExpand
Some aspects of melanin biology: 1950-1975.
TLDR
The current state of knowledge of the form and function of epidermal melanin units is examined from the levels of biologic organization ranging from the molecules relevant to melanin synthesis through the skin as a totally intergrated system. Expand
Comparison of eumelanogenesis and pheomelanogenesis in retinal and follicular melanocytes; role of vesiculo-globular bodies in melanosome differentiation.
TLDR
The mode of their involvement in melanosomal differentiation was studied by ultrastructural comparison of eu- and pheomelanogenesis occurring in retinal and follicular melanocytes, found that the number and distribution of these bodies differ significantly with types of melanogenesis and tissues. Expand
...
1
2
3
4
5
...