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Aldesleukin

Known as: Interleukin-2(2-133),125-ser, aldesleukin [Chemical/Ingredient], Recombinant Human IL-2 
A recombinant analog of the endogenous cytokine interleukin-2 (IL-2) with immunoregulatory and antineoplastic activities. Aldesleukin binds to and… 
National Institutes of Health

Related topics

Related topics

46 relations
Aldesleukin 22000000 UNT Injection [Proleukin]Biomed 101/interleukin-2Cardiac TamponadeDecreased Ventilatory Gas Flow [PE]

Broader (3)

Anti-HIV AgentsAntineoplastic AgentsRecombinant Proteins

Narrower (1)

Proleukin

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2002
Highly Cited
2002
Release of recombinant human interleukin-2 from dextran-based hydrogels.
Highly Cited
1998
Highly Cited
1998
Characterization of a novel human natural killer-cell line (NK-YS) established from natural killer cell lymphoma/leukemia associated with Epstein-Barr virus infection.
A novel cell line was established from a patient with a leukemic-state nasal angiocentric natural killer (NK) cell lymphoma with… 
Highly Cited
1997
Highly Cited
1997
Regulation of local host-mediated anti-tumor mechanisms by cytokines: direct and indirect effects on leukocyte recruitment and angiogenesis.
The regulation of tumor growth by cytokine-induced alterations in host effector cell recruitment and activation is intimately… 
Highly Cited
1995
Highly Cited
1995
Adoptive immunotherapy with tumor-infiltrating lymphocytes and interleukin-2 in patients with metastatic malignant melanoma and renal cell carcinoma: a pilot study.
PURPOSE The objective of this study was to determine the tolerance and effect of moderate-dose recombinant human interleukin-2… 
Highly Cited
1992
Highly Cited
1992
Membrane-based receptor affinity chromatography.
1992
1992
Inhibition of CD25 (IL-2R alpha) expression and T-cell proliferation by polyclonal anti-thymocyte globulins.
Anti-lymphocyte and anti-thymocyte globulins (ATG) are currently used as immunosuppressive agents in organ transplantation. Their… 
Highly Cited
1991
Highly Cited
1991
Increased lymphocyte beta‐adrenergic receptor density in progressive multiple sclerosis is specific for the CD8+, CD28− suppressor cell
Beta‐adrenergic receptor density on T cells from healthy humans is greatest on suppressor cells (CD8+, CD28−) and the effect of… 
1990
1990
Production of recombinant human interleukin-2 with BHK cells in a hollow fibre and a stirred tank reactor with protein-free medium.
Highly Cited
1987
Highly Cited
1987
Prophylactic administration of interleukin-2 protects mice from lethal challenge with gram-negative bacteria
Prophylactic administration of recombinant human interleukin-2 (IL-2) in mice enhanced survival and produced complete recovery… 
Highly Cited
1984
Highly Cited
1984
Systemic administration of recombinant human interleukin-2 in mice.
The production of recombinant human interleukin-2 (RIL-2) in large amounts has made possible studies of the in vivo effects of… 
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