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Cardiotonic Agents

Known as: Cardioprotective Agent, cardiac stimulant, Myocardial Stimulants 
Agents that have a strengthening effect on the heart or that can increase cardiac output. They may be CARDIAC GLYCOSIDES; SYMPATHOMIMETICS; or other… 
National Institutes of Health

Related topics

Related topics

46 relations

Narrower (38)

6-hydroxymelatoninAcetyldigitoxinsAminophyllineBDF 9148

Broader (2)

Cardiovascular AgentsPharmaceutical Preparations
In BloodMyocardial ContractionNorepinephrineagonists

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2013
Review
2013
Current State of Clinical Translation of Cardioprotective Agents for Acute Myocardial Infarction
There is continued interest in the concept of limiting myocardial infarct size with adjunctive agents administered along with… 
Review
2004
Review
2004
Structural based insights into the role of troponin in cardiac muscle pathophysiology
Abstract Troponin is a molecular switch, directly regulating the Ca2+-dependent activation of myofilament in striated muscle… 
Highly Cited
1998
Highly Cited
1998
Ca2+ flux through promiscuous cardiac Na+ channels: slip-mode conductance.
The tetrodotoxin-sensitive sodium ion (Na+) channel is opened by cellular depolarization and favors the passage of Na+ over other… 
Highly Cited
1998
Highly Cited
1998
Structure of human adenosine kinase at 1.5 A resolution.
Adenosine kinase (AK) is a key enzyme in the regulation of extracellular adenosine and intracellular adenylate levels. Inhibitors… 
Highly Cited
1997
Highly Cited
1997
Delayed administration of dexrazoxane provides cardioprotection for patients with advanced breast cancer treated with doxorubicin-containing therapy.
PURPOSE To assess whether dexrazoxane (DZR) given after a cumulative doxorubicin dose of 300 mg/m2 confers cardioprotection in… 
Highly Cited
1983
Highly Cited
1983
Characterization of the Cardiotonic Effects of Milrinone, a New and Potent Cardiac Bipyridine, on Isolated Tissues from Several Animal Species
The cardiotonic activity of milrinone (Win 47203), a potent analogue of amrinone, was demonstrated in isolated guinea pig, cat… 
Highly Cited
1982
Highly Cited
1982
Biochemical Studies on the Mechanism of Cardiotonic Activity of MDL 17,043
MDL 17.043 (1,3-dihydro-4-methyl-5-[4-(methylthio)-benzoyl]-2H-imidazol-2-one) is a new drug with cardiotonic properties. Its… 
Highly Cited
1979
Highly Cited
1979
Cardiotonic Activity of Amrinone–Win 40680 [5‐Amino‐3,4f‐bipyridin‐6(lH)‐one]
The cardiotonic activity of a new, noncatechol, nonglycoside agent, amrinone, waa investigated in vitro and in anesthestized and… 
Highly Cited
1979
Highly Cited
1979
Inotropic and arrhythmogenic effects of potassium‐depleted solutions on mammalian cardiac muscle.
1. We have investigated the electrical and mechanical effects of reducing the bathing K concentration, K0, over the range from 4… 
Highly Cited
1970
Highly Cited
1970
On the reversibility of binding of cardiotonic steroids to a partially purified (Na+K)-activated adenosinetriphosphatase from beef brain.
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