Anti-HIV benzylisoquinoline alkaloids and flavonoids from the leaves of Nelumbo nucifera, and structure-activity correlations with related alkaloids.
Chemical Constituents of Murraya euchrestifolia HAYATA. Structures of Novel Carbazolequinones and Other New Carbazole Alkaloids
Thirteen carbazole alkaloids were isolated from Murraya euchrestifolia HAYATA (Rutaceae) collected in Taiwan. Four of them are novel carbazolequinones [murrayaquinone-A (7), -B (8), -C (9), and -D…
Cancer chemopreventive agents, 4-phenylcoumarins from Calophyllum inophyllum.
Chemical constituents of Calophyllum brasiliensis: structure elucidation of seven new xanthones and their cancer chemopreventive activity.
Among the xanthones isolated in this study, 4, 5, 6, and 11 were found to exhibit significant inhibitory activity against 12-O-tetradecanoylphorbol-13-acetate induced Epstein-Barr virus early antigen activation in Raji cells.
Chemical constituents of Clausena excavata: isolation and structure elucidation of novel furanone-coumarins with inhibitory effects for tumor-promotion.
These furanone-coumarins were found to exhibit inhibitory activity against 12-O-tetradecanoylphorbol-13-acetate-induced Epstein-Barr virus early antigen activation in Raji cells, the first example of coumarins with these structural characteristics in nature.
Chemical constituents of Glycosmis arborea: three new carbazole alkaloids and their biological activity.
As a primary screening test for anti-tumor promoters, nine alkaloids isolated from this plant have been tested for their inhibitory effects on Epstein-Barr virus early antigen (EBV-EA) induction by the tumor promoter 12-O-tetradecanoylphorbol-13-acetate (TPA).
Antitumor agents. 203. Carbazole alkaloid murrayaquinone A and related synthetic carbazolequinones as cytotoxic agents.
Murrayaquinone A and murrayafoline A, isolated from the root bark of Murraya euchrestifolia, were identified as cytotoxic compounds and exhibited marginal or weak cytotoxicity against SK-MEL-5, Colo-205, HCT-8, KB, and A-549 tumor cell lines.
Induction of apoptosis by carbazole alkaloids isolated from Murraya koenigii.
Chemical constituents of Garcinia fusca: structure elucidation of eight new xanthones and their cancer chemopreventive activity.
All the new xanthones were shown to have a terpenoid (prenyl and/or geranyl) side chain(s) in their molecules.