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Test for carcinogenicity of food additives and chemotherapeutic agents by the pulmonary tumor response in strain A mice.
Summary Forty-one food additives and 20 chemotherapeutic agents were examined for their ability to induce primary lung tumors in A mice. The animals received i.p. injections of each compound for 8Expand
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Differential effects of CYP2E1 status on the metabolic activation of the colon carcinogens azoxymethane and methylazoxymethanol.
Methylazoxymethanol (MAM) and its chemical and metabolic precursor, azoxymethane (AOM), both strong colon carcinogens in rodents, can be metabolically activated by CYP2E1 in vitro. Using CYP2E1-nullExpand
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Tea and health: a historical perspective.
In many parts of the world, green tea and black tea are produced from the plant Camellia sinensis. Tea is one of the most widely consumed beverages, second only to water. It is one of the safestExpand
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Testing of twenty-one environmental aromatic amines or derivatives for long-term toxicity or carcinogenicity.
Twenty-one aromatic amines or derivatives were tested for long-term toxicity by dietary administration to male Charles River rats and male and female HaM/lCR mice. 2,4-Toluenediamine,Expand
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Carcinogenicity tests of certain environmental and industrial chemicals.
Fourteen chemicals of varied uses were tested for carcinogenicity by oral administration in male and female Charles River CD rats. Under the conditions of the tests, propane sultone, propylene imine,Expand
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The Dietitian's Guide to Vegetarian Diets
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Nutrition and its relationship to cancer.
Publisher Summary Nutrition is related to the development of cancer in three ways: (1) food additives or contaminants may act as carcinogens, cocarcinogens, or both; (2) nutrient deficiencies mayExpand
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Colon carcinogens: Their metabolism and mode of action
Colon cancer in man almost certainly is induced by environmental factors, probably consumed with food. Except for one breed of hamsters, colon cancer is infrequent in laboratory or domestic animals.Expand
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Effects of green and black tea on hepatic xenobiotic metabolizing systems in the male F344 rat.
1. The induction of phase I and II enzymes in the liver of the male F344 rat drinking 2% (w/v) solutions of green or black tea for 6 weeks was investigated. Also studied were glutathione (GSH) andExpand
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