topiramate

Known as: Tipiramate, 2,3:4,5-Bis-O-(1-methylethylidene)-beta-D-fructopyranose sulfamate, beta-D-Fructopyranose, 2,3:4,5-bis-O-(1-methylethylidene)-, Sulfamate 
A sulfamate-substituted monosaccharide with anticonvulsant property. Although the mechanism of action has not been fully elucidated, topiramate… (More)

Topic mentions per year

Topic mentions per year

1973-2017
020040019732017

Papers overview

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Highly Cited
2011
Highly Cited
2011
Inflammatory bowel disease (IBD) is a chronic inflammatory disorder of the gastrointestinal tract for which there are few safe… (More)
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Highly Cited
2011
Highly Cited
2011
BACKGROUND Obesity is associated with a reduction in life expectancy and an increase in mortality from cardiovascular diseases… (More)
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Highly Cited
2007
Highly Cited
2007
BACKGROUND Valproate is widely accepted as a drug of first choice for patients with generalised onset seizures, and its broad… (More)
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Highly Cited
2007
Highly Cited
2007
CONTEXT Hypothetically, topiramate can improve drinking outcomes among alcohol-dependent individuals by reducing alcohol's… (More)
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Highly Cited
2007
Highly Cited
2007
BACKGROUND Carbamazepine is widely accepted as a drug of first choice for patients with partial onset seizures. Several newer… (More)
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Highly Cited
2007
Highly Cited
2007
OBJECTIVE To evaluate the efficacy and safety of topiramate (100 mg/day) compared with placebo for the treatment of chronic… (More)
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Highly Cited
2007
Highly Cited
2007
The aim of this study was to evaluate the efficacy and tolerability of topiramate for the prevention of chronic migraine in a… (More)
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Highly Cited
2004
Highly Cited
2004
BACKGROUND Open-label trials and small controlled studies report topiramate's efficacy in migraine prevention. OBJECTIVE To… (More)
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Highly Cited
2004
Highly Cited
2004
CONTEXT Small open-label and controlled trials suggest that the antiepileptic drug topiramate is effective for migraine… (More)
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Highly Cited
2003
Highly Cited
2003
BACKGROUND Topiramate, a sulphamate fructopyranose derivative, might antagonise alcohol's rewarding effects associated with abuse… (More)
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