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topiramate

Known as: Tipiramate, 2,3:4,5-Bis-O-(1-methylethylidene)-beta-D-fructopyranose sulfamate, beta-D-Fructopyranose, 2,3:4,5-bis-O-(1-methylethylidene)-, Sulfamate 
A sulfamate-substituted monosaccharide with anticonvulsant property. Although the mechanism of action has not been fully elucidated, topiramate… 
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
Measures of RNA abundance are important for many areas of biology and often obtained from high-throughput RNA sequencing methods… 
Highly Cited
2011
Highly Cited
2011
Computationally predicted repositioning of an anticonvulsant for inflammatory bowel disease is confirmed experimentally. Greening… 
Highly Cited
2007
Highly Cited
2007
CONTEXT Hypothetically, topiramate can improve drinking outcomes among alcohol-dependent individuals by reducing alcohol's… 
Highly Cited
2007
Highly Cited
2007
The aim of this study was to evaluate the efficacy and tolerability of topiramate for the prevention of chronic migraine in a… 
Highly Cited
2004
Highly Cited
2004
CONTEXT Small open-label and controlled trials suggest that the antiepileptic drug topiramate is effective for migraine… 
Highly Cited
2004
Highly Cited
2004
BACKGROUND Open-label trials and small controlled studies report topiramate's efficacy in migraine prevention. OBJECTIVE To… 
Highly Cited
2003
Highly Cited
2003
OBJECTIVE Binge eating disorder is associated with obesity. Topiramate is an antiepileptic agent associated with weight loss. The… 
Review
2000
Review
2000
In this overview, we discuss the discovery and development of topiramate (TPM) as an anticonvulsant, including notable aspects of…