Antiepileptic Agents

Background: Antiepileptic drugs (AEDs) are the mainstay of epilepsy treatment. Since 1989, 18 new AEDs have been licensed for… Expand

CONTEXT Despite reported success, surgery for pharmacoresistant seizures is often seen as a last resort. Patients are typically… Expand

To describe a distinctive seizure semiology that closely associates with voltage‐gated potassium channel (VGKC)‐complex/Lgi1… Expand

Although no randomized studies have demonstrated a positive impact of therapeutic drug monitoring (TDM) on clinical outcome in… Expand

Some patients with difficult-to-treat epilepsy benefit from combination therapy with two or more antiepileptic drugs (AEDs… Expand

Epilepsy is the most common neurological disorder of young humans. Each year 150,000 children in the United States experience… Expand

As part of a large community‐based study, we retrospectively examined the clinical course of epilepsy in an unselected population… Expand

Summary: Why some patients with seizures are successfully treated with antiepileptic drugs (AEDs) and others prove medically… Expand

Summary: Using univariate and multivariate regression analysis, we studied seizure duration, seizure type, age, etiologies, other… Expand

Summary: Vagus nerve stimulation (VNS) was shown to reduce seizure frequency in refractory epilepsy patients in two pilot studies… Expand