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Neuroprotective Agents

Known as: Neuroprotectants, Neuroprotective Agent, neuroprotective drug 
Drugs intended to prevent damage to the brain or spinal cord from ischemia, stroke, convulsions, or trauma. Some must be administered before the… 
National Institutes of Health

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Narrower (42)

1-aminocyclopropane-1-carboxylic acid3-aminobenzamide3-n-butylphthalide4-carboxy-3-hydroxyphenylglycine
ChemopreventionIn Bloodagonistsantagonists & inhibitors

Broader (1)

neuropharmacologic agent

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Adaptive Brain Shut-Down Counteracts Neuroinflammation in the Near-Term Ovine Fetus
Objective: Repetitive umbilical cord occlusions (UCOs) in ovine fetus leading to severe acidemia result in adaptive shut-down of… 
2012
2012
Behavioural studies with a newly developed neuroprotective KYNA-amide
The neuroactive properties and neuroprotective potential of endogenous l-kynurenine, kynurenic acid (KYNA) and its derivatives… 
Review
2011
Review
2011
Trafermin for stroke recovery: is it time for another randomized clinical trial?
Introduction: Basic fibroblast growth factor (bFGF) has been shown to reduce volume in acute ischemic stroke models, and to… 
2009
2009
Excitotoxic motoneuron degeneration induced by glutamate receptor agonists and mitochondrial toxins in organotypic cultures of chick embryo spinal cord
Glutamate receptor‐mediated excitotoxicity and mitochondrial dysfunction appear to play an important role in motoneuron (MN… 
2008
2008
Effect of intravenous calcium and magnesium (IV CaMg) on oxaliplatin-induced sensory neurotoxicity (sNT) in adjuvant colon cancer: Results of the phase III placebo-controlled, double-blind NCCTG…
4009 Background: Cumulative sNT is the dose-limiting toxicity of oxaliplatin which commonly leads to early discontinuation of… 
Review
2008
Review
2008
Treating acute ischemic stroke.
Acute ischemic stroke (AIS) is a common disorder that has only one associated approved therapy: intravenous tissue plasminogen… 
2004
2004
A paradigm shift for erythropoietin: no longer a specialized growth factor, but rather an all-purpose tissue-protective agent
A paradigm shift for erythropoietin: no longer a specialized growth factor, but rather an all-purpose tissue-protective agent 
2002
2002
Clinical trial of the neuroprotectant clomethiazole in coronary artery bypass graft surgery: a randomized controlled trial.
BACKGROUND The neuroprotective property of clomethiazole has been demonstrated in several animal models of global and focal brain… 
2002
2002
Enhanced protection by melatonin and meloxicam combination in a middle cerebral artery occlusion model of acute ischemic stroke in rat.
Mixed efficacy of neuroprotective drugs in clinical trials has led to the emergence of the approach of combination therapy in… 
2000
2000
Dopaminergic denervation enhances susceptibility to hydroxyl radicals in rat neostriatum
Summary. To determine if greater amounts of hydroxyl radical (•OH) are formed by dopamine (DA) denervation and treatment with L… 
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