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Traumatic brain injury (TBI) is a leading cause of mortality and morbidity both in civilian life and on the battlefield worldwide… Expand Acute ischemic stroke is the third leading cause of death in industrialized countries and the most frequent cause of permanent… Expand Preclinical evaluation of neuroprotectants fostered high expectations of clinical efficacy. When not matched, the question arises… Expand Background and Purpose— The National Institutes of Health (NIH) estimates that stroke costs now exceed $45 billion per year… Expand 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) damages the nigrostriatal dopaminergic pathway as seen in Parkinson's disease… Expand Background— Neuroprotective drugs for acute stroke have appeared to work in animals, only to fail when tested in humans. With the… Expand The plethora of failed clinical trials with neuroprotective drugs for acute ischemic stroke have raised justifiable concerns… Expand BACKGROUND AND PURPOSE
The Barthel Index (BI) and the Modified Rankin Scale (MRS) are commonly used scales that measure… Expand The neuroprotective actions of cannabidiol and other cannabinoids were examined in rat cortical neuron cultures exposed to toxic… Expand 2,3-Dihydroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline (NBQX) is an analog of the quinoxalinedione antagonists to the non-N-methyl… Expand