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3-n-butylphthalide

Known as: 3-BUTYLPHTHALIDE, BUTYLPHTHALIDE, l-NBP cpd 
 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (3)

BenzofuransNeuroprotective AgentsPlatelet Aggregation Inhibitors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
3-N-Butylphthalide (NBP) Attenuates the Amyloid-ß-Induced Inflammatory Responses in Cultured Astrocytes via the Nuclear Factor-κB Signaling Pathway
Background/Aims: Activation of astrocytes is a common feature of Alzheimer's disease (AD). Proinflammatory molecules produced by… Expand
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Highly Cited
2013
Highly Cited
2013
Ninety‐day administration of dl‐3‐n‐butylphthalide for acute ischemic stroke: a randomized, double‐blind trial
Background Dl‐3‐n‐butylphthalide (NBP), first isolated from the seeds of celery, showed efficacy in animal models of stroke. This… Expand
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Highly Cited
2012
Highly Cited
2012
Dl-3-n-butylphthalide, a natural antioxidant, protects dopamine neurons in rotenone models for Parkinson's disease
In the absence of a cure for Parkinson's disease, development of preventive medications for this devastating disease is… Expand
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Highly Cited
2012
Highly Cited
2012
dl-3-n-butylphthalide extends survival by attenuating glial activation in a mouse model of amyotrophic lateral sclerosis
Amyotrophic lateral sclerosis (ALS) is a lethal neurodegenerative disease characterized by progressive muscular atrophy… Expand
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Highly Cited
2010
Highly Cited
2010
l-3-n-Butylphthalide Improves Cognitive Impairment and Reduces Amyloid-β in a Transgenic Model of Alzheimer's Disease
Alzheimer's disease (AD) is an age-related, progressive neurodegenerative disorder that occurs gradually and results in memory… Expand
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Highly Cited
2010
Highly Cited
2010
dl-3-n-Butylphthalide prevents neuronal cell death after focal cerebral ischemia in mice via the JNK pathway
DL-3-n-Butylphthalide (NBP) has shown cytoprotective effects in animal models of stroke and has passed clinical trials as a… Expand
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Highly Cited
2010
Highly Cited
2010
dl-3-n-Butylphthalide prevents oxidative damage and reduces mitochondrial dysfunction in an MPP+-induced cellular model of Parkinson's disease
The aim of the present study was to explore the neuroprotective effects and mechanisms of action of dl-3-n-butylphthalide (NBP… Expand
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Highly Cited
2009
Highly Cited
2009
dl-3-n-butylphthalide protects endothelial cells against oxidative/nitrosative stress, mitochondrial damage and subsequent cell death after oxygen glucose deprivation in vitro
DL-3-n-butylphthalide (NBP) has been used for stroke treatment in China for years. Recently, we found that NBP can reduce the… Expand
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Highly Cited
2009
Highly Cited
2009
Identification and determination of the major constituents in Traditional Chinese Medicinal formula Danggui-Shaoyao-San by HPLC-DAD-ESI-MS/MS.
Danggui-Shaoyao-San (DSS), a famous traditional Chinese medicine formula consisting of six herbal medicines (Paeonia lactiflora… Expand
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Highly Cited
2007
Highly Cited
2007
l-3-n-Butylphthalide Improves Cognitive Impairment Induced by Chronic Cerebral Hypoperfusion in Rats
3-n-Butylphthalide (NBP) may be beneficial for the treatment of ischemic stroke with multiple actions on different… Expand
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