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Antiepileptic drugs—best practice guidelines for therapeutic drug monitoring: A position paper by the subcommission on therapeutic drug monitoring, ILAE Commission on Therapeutic Strategies
Although no randomized studies have demonstrated a positive impact of therapeutic drug monitoring (TDM) on clinical outcome in epilepsy, evidence from nonrandomized studies and everyday clinicalExpand
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Therapeutic Drug Monitoring of the Newer Antiepileptic Drugs
The aim of the present review is to discuss the potential value of therapeutic drug monitoring (TDM) of the newer antiepileptic drugs (AEDs) felbamate, gabapentin, lamotrigine, levetiracetam,Expand
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Valproate: past, present, and future.
Preclinical studies have been carried out during the past four decades to investigate the different mechanisms of action of valproate (VPA). The mechanisms of VPA which seem to be of clinicalExpand
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Antiepileptic Drug Interactions - Principles and Clinical Implications
Antiepileptic drugs (AEDs) are widely used as long-term adjunctive therapy or as monotherapy in epilepsy and other indications and consist of a group of drugs that are highly susceptible to drugExpand
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Pharmacokinetic Variability of Newer Antiepileptic Drugs
A new generation of antiepileptic drugs (AEDs) has reached the market in recent years with ten new compounds: felbamate, gabapentin, lamotrigine, levetiracetam, oxcarbazepine, pregabalin, tiagabine,Expand
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Progress report on new antiepileptic drugs: A summary of the Eleventh Eilat Conference (EILAT XI)
The Eleventh Eilat Conference on New Antiepileptic Drugs (AEDs)-EILAT XI, took place in Eilat, Israel from the 6th to 10th of May 2012. About 100 basic scientists, clinical pharmacologists andExpand
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A paradoxical effect of levetiracetam may be seen in both children and adults with refractory epilepsy
The aim of this prospective, uncontrolled clinical study was to evaluate the tolerability and the efficacy of levetiracetam as add-on treatment in 78 adults and 44 children with intractable epilepsy.Expand
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Commission on European Affairs: Appropriate Standards of Epilepsy Care Across Europe
The countries of Europe have widely varying structures and systems for the provision of health care. Emphasis differs in the balance between primary and secondary care; the provision of inpatient andExpand
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Progress report on new antiepileptic drugs: A summary of the Thirteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XIII)
The Thirteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XIII) took place in Madrid, Spain, on June 26–29, 2016, and was attended by >200 delegates from 31 countries. The presentExpand
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Therapeutic monitoring of the new antiepileptic drugs
AbstractObjective: To discuss the potential value of therapeutic drug monitoring (TDM) of the new antiepileptic drugs gabapentin, lamotrigine, oxcarbazepine, tiagabine, topiramate, vigabatrin andExpand
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