romidepsin

Known as: N-[(3S,4E-3-Hydroxy-7-mercapto-1-oxo-4-heptenyl]-D-valyl-D-cysteinyl-(2Z)-2-amino-2-butenoyl-L-valine, (4->1) Lactone, Cyclic, L-Valine, N-(3-Hydroxy-7-Mercapto-1-Oxo-4-Heptenyl)-D-Valyl-D-Cysteinyl-(Z)-2,3 -Didehydro-2-Aminobutanoyl-, xi-Lactone, Cyclic (1-2)-Disulfide, (S-(E))-, L-Valine, N-(3-hydroxy-7-mercapto-1-oxo-4-heptenyl)-D-valyl-D-cysteinyl-(Z)-2,3-didehydro-2-aminobutanoyl-, xi-lactone, cyclic (1-2)-disulfide, (S-(E))- 
A bicyclic depsipeptide antibiotic isolated from the bacterium Chromobacterium violaceum with antineoplastic activity. After intracellular activation… (More)
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2015
Highly Cited
2015
UNLABELLED Pharmacologically-induced activation of replication competent proviruses from latency in the presence of… (More)
  • figure 1
  • table 1
  • table 2
  • figure 2
  • figure 3
Is this relevant?
Highly Cited
2014
Highly Cited
2014
Persistent latent reservoir of replication-competent proviruses in memory CD4 T cells is a major obstacle to curing HIV infection… (More)
  • figure 1
  • table 1
  • table 2
  • figure 2
  • figure 3
Is this relevant?
Review
2014
Review
2014
Epigenetic enzymes are often dysregulated in human tumors through mutation, altered expression, or inappropriate recruitment to… (More)
  • table 1
  • figure 1
  • table 2
  • figure 2
Is this relevant?
Highly Cited
2011
Highly Cited
2011
Romidepsin (depsipeptide or FK228) is a histone deacetylase inhibitor, one of a new class of agents active in T-cell lymphoma. A… (More)
  • table 2
  • table 1
  • table 3
  • table 4
  • table 5
Is this relevant?
Highly Cited
2010
Highly Cited
2010
PURPOSE The primary objective of this study was to confirm the efficacy of romidepsin in patients with treatment refractory… (More)
Is this relevant?
Highly Cited
2009
Highly Cited
2009
PURPOSE Romidepsin (depsipeptide or FK228) is a member of a new class of antineoplastic agents active in T-cell lymphoma, the… (More)
Is this relevant?
Highly Cited
2005
Highly Cited
2005
Recent studies have described malignant stem cells as central to the initiation, growth, and potential relapse of acute and… (More)
  • table 1
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Review
2004
Review
2004
Rapamycin, a macrocyclic lactone, is a highly specific inhibitor of the serine/threonine protein kinase target of rapamycin (TOR… (More)
  • figure 1
  • figure 3
  • figure 2
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2003
Highly Cited
2003
Artemisinins are extracted from sweet wormwood (Artemisia annua) and are the most potent antimalarials available, rapidly killing… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 1
Is this relevant?
Highly Cited
2000
Highly Cited
2000
N-acylhomoserine lactones, known as autoinducers (AIs), are widely conserved signal molecules present in quorum-sensing systems… (More)
  • figure 2
  • figure 1
  • figure 3
  • table 1
  • table 2
Is this relevant?