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romidepsin

Known as: N-[(3S,4E-3-Hydroxy-7-mercapto-1-oxo-4-heptenyl]-D-valyl-D-cysteinyl-(2Z)-2-amino-2-butenoyl-L-valine, (4->1) Lactone, Cyclic, L-Valine, N-(3-Hydroxy-7-Mercapto-1-Oxo-4-Heptenyl)-D-Valyl-D-Cysteinyl-(Z)-2,3 -Didehydro-2-Aminobutanoyl-, xi-Lactone, Cyclic (1-2)-Disulfide, (S-(E))-, L-Valine, N-(3-hydroxy-7-mercapto-1-oxo-4-heptenyl)-D-valyl-D-cysteinyl-(Z)-2,3-didehydro-2-aminobutanoyl-, xi-lactone, cyclic (1-2)-disulfide, (S-(E))- 
A bicyclic depsipeptide antibiotic isolated from the bacterium Chromobacterium violaceum with antineoplastic activity. After intracellular activation… Expand
National Institutes of Health

Papers overview

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Review
2018
Review
2018
ABSTRACT In the framework of the FP7 ECsafeSeafood project, 62 seafood samples commercialized in Europe Union from several… Expand
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Review
2017
Review
2017
Infestations with the cattle tick, Rhipicephalus microplus, constitute the most important ectoparasite problem for cattle… Expand
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Highly Cited
2011
Highly Cited
2011
Romidepsin (depsipeptide or FK228) is a histone deacetylase inhibitor, one of a new class of agents active in T-cell lymphoma. A… Expand
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Highly Cited
2010
Highly Cited
2010
PURPOSE The primary objective of this study was to confirm the efficacy of romidepsin in patients with treatment refractory… Expand
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Highly Cited
2009
Highly Cited
2009
PURPOSE Romidepsin (depsipeptide or FK228) is a member of a new class of antineoplastic agents active in T-cell lymphoma, the… Expand
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Review
2004
Review
2004
Rapamycin, a macrocyclic lactone, is a highly specific inhibitor of the serine/threonine protein kinase target of rapamycin (TOR… Expand
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Highly Cited
2003
Highly Cited
2003
Artemisinins are extracted from sweet wormwood (Artemisia annua) and are the most potent antimalarials available, rapidly killing… Expand
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Highly Cited
1998
Highly Cited
1998
Synthesis of Alpha-Diazocarbonyl Compounds. Catalysts for Metal Carbene Transformations. Insertion Reactions. Intermolecular… Expand
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Highly Cited
1990
Highly Cited
1990
Thapsigargin, a tumor-promoting sesquiterpene lactone, discharges intracellular Ca2+ in rat hepatocytes, as it does in many… Expand
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Highly Cited
1981
Highly Cited
1981
Synthesis of bacterial luciferase in some strains of luminous bacteria requires a threshold concentration of an autoinducer… Expand
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