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New genus of the Actinomycetales: Streptoalloteichus hindustanus gen. nov., nom. rev.; sp. nov., nom. rev.
Chemotaxonomically, this organism is related to Saccharothrix australiensis, while it is differentiated by its Streptomyces-type morphology. Expand
Structure of 3-isopropylmalate dehydrogenase in complex with 3-isopropylmalate at 2.0 A resolution: the role of Glu88 in the unique substrate-recognition mechanism.
The crystal structure of IPMDH is determined from Thiobacillus ferrooxidans complexed with 3-isopropylmalate (IPM) at 2.0 and shows a fully closed conformation and the substrate-binding site is quite similar to that of ICDH except for a region around the gamma-isOPropyl group. Expand
Streptoalloteichus, a new genus of the family Actinoplanaceae.
A new genus Streptoalloteichus is proposed in the family Actinoplanaceae to distinguish species of actinomycetes which form short or long spore-chains on aerial mycelium, bears oval sporangia withExpand
Pradimicin, a novel class of potent antifungal antibiotics.
Tallysomycin, a new antitumor antibiotic complex related to bleomycin. I. Production, isolation and properties.
Tallysomycin exhibited broad antibacterial and antifungal activity, and was highly active in vivo against bacterial infections in mice, and demonstrated potent activity in the prophage induction of lysogenic bacteria. Expand
Empedopeptin (BMY-28117), a new depsipeptide antibiotic. I. Production, isolation and properties.
Empedopeptin is a new antibiotic produced by empedobacter haloabium nov. sp. (ATCC 31962). It is a water-soluble depsipeptide antibiotic containing eight amino acid residues and a C14-fatty acidExpand
Cispentacin, a new antifungal antibiotic. I. Production, isolation, physico-chemical properties and structure.
A new antibiotic, cispentacin, was isolated from the culture broth of a Bacillus cereus strain, L450-B2, and demonstrated only weak in vitro activity against certain fungi but strong protection of mice from lethal infection of Candida albicans A9540. Expand
BB-K 8, a new semisynthetic aminoglycoside antibiotic.
BB-K8 is a new derivative of kanamycin acylated with L(-)-γ-γ-amino-α-hydroxybutyric acid at the C-1 amino group of the 2-deoxystreptamine moiety that has antibacterial activity generally equal to Kanamycin againstkanamycin-sensitive organisms and is also active against kan amycin- and/or gentamicin-resistant organisms, including Pseudomonas strains. Expand
Molecular weight variations in the diversity of phospholipase A2 forms in reptile venoms.
A radiolabeling technique has been developed which allows detection of phospholipase A2 enzymes after electrophoretic separation on the basis of molecular weight in polyacrylamide gels containing sodium dodecylsulfate, and results are consistent with diversity in reptile venom phospholips A2 forms being derived from differences in both molecular weight and charge. Expand