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Pumilacidin, a complex of new antiviral antibiotics. Production, isolation, chemical properties, structure and biological activity.
New antibiotic pumilacidin components were inhibitory to herpes simplex virus type 1 and H+, K(+)-ATPase and demonstrated antiulcer activity in rat. Expand
Pumilacidin components were inhibitory to herpes simplex virus type 1 and H+, K+-ATPase and demonstrated antiulcer activity in rat. Expand
Highly cytotoxic metabolites from the culture supernatant of the temperate dinoflagellate Protoceratium cf. reticulatum.
In the course of our search for antitumor compounds in dinoflagellates, the culture broths of two strains of Protoceratium cf. reticulatum showed extremely potent cytotoxicity against human tumorExpand
Pradimicin, a novel class of potent antifungal antibiotics.
Tallysomycin, a new antitumor antibiotic complex related to bleomycin. I. Production, isolation and properties.
Tallysomycin exhibited broad antibacterial and antifungal activity, and was highly active in vivo against bacterial infections in mice, and demonstrated potent activity in the prophage induction of lysogenic bacteria. Expand
Sultriecin, a new antifungal and antitumor antibiotic from Streptomyces roseiscleroticus. Production, isolation, structure and biological activity.
Streptomyces roseiscleroticus L827-7 (ATCC 53903) produced a novel antifungal and antitumor antibiotic, sultriecin. It exhibited in vitro antifungal activity and potent in vivo antitumor activityExpand
Empedopeptin (BMY-28117), a new depsipeptide antibiotic. I. Production, isolation and properties.
Empedopeptin is a new antibiotic produced by empedobacter haloabium nov. sp. (ATCC 31962). It is a water-soluble depsipeptide antibiotic containing eight amino acid residues and a C14-fatty acidExpand
Cispentacin, a new antifungal antibiotic. I. Production, isolation, physico-chemical properties and structure.
A new antibiotic, cispentacin, was isolated from the culture broth of a Bacillus cereus strain, L450-B2, and demonstrated only weak in vitro activity against certain fungi but strong protection of mice from lethal infection of Candida albicans A9540. Expand
Epoxomicin, a new antitumor agent of microbial origin.
An actinomycete strain No. Q996-17 produced a novel compound, epoxomicin, which exhibited in vivo antitumor activity against B16 melanoma. Structural studies indicated that it is a new member of theExpand