Istodax

Known as: Astella Pharma Brand of romidepsin 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2009-2017
024620092017

Papers overview

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2017
2017
Histone deacetylases (HDACs) are validated targets for treatment of certain cancer types and play numerous regulatory roles in… (More)
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2017
2017
Increased expression of the pro-angiogenic chemokine interleukin-8 (CXCL8, IL-8) contributes to the progression of solid cancers… (More)
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2015
2015
The therapeutic action of drugs is predicated on their physical engagement with cellular targets. Here we describe a broadly… (More)
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Review
2014
Review
2014
Histone deacetylases (HDACs) are widely studied targets for the treatment of cancer and other diseases. Up to now, over twenty… (More)
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2013
2013
Inflammatory breast cancer (IBC) is the most metastatic variant of locally advanced breast cancer. IBC has distinctive… (More)
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2012
2012
partnership on the discovery, development and commercialization of inhibitors of histone methyltransferases (HMTs), an emerging… (More)
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2011
2011
Histone deacetylase (HDAC) inhibitors have emerged as a new class of anticancer drugs, with one synthetic compound, SAHA… (More)
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2011
2011
Histone deacetylases (HDACs) are important epigenetic factors regulating a variety of vital cellular functions such as cell cycle… (More)
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Review
2011
Review
2011
Romidepsin (Istodax), a selective inhibitor of histone deacetylases (HDACs), was approved for the treatment of cutaneous T-cell… (More)
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2011
2011
Bioactivity-guided fractionation of an extract of Burkholderia thailandensis led to the isolation and identification of a new… (More)
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