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Histone Deacetylase

Known as: Histone Deacetylases, HDAC Proteins, Deacetylases, Histone 
Histone acetylation and deacetylation alternately exposes and occludes DNA to transcription factors. Histone deacetylation is catalyzed by the… Expand
National Institutes of Health

Papers overview

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Review
2019
Review
2019
Short-chain fatty acids (SCFAs), the main metabolites produced by bacterial fermentation of dietary fibre in the gastrointestinal… Expand
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Review
2019
Review
2019
Glutamate is the primary excitatory neurotransmitter in the central nervous system (CNS) which initiates rapid signal… Expand
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Review
2019
Review
2019
Histone deacetylases (HDACs), encompassing at least 18 members, are promising targets for anticancer drug discovery and… Expand
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Review
2019
Review
2019
A multitude of new agents for the treatment of hematologic malignancies has been introduced over the past decade. Hematologists… Expand
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Review
2019
Review
2019
Packaging the long and fragile genomes of eukaryotic species into nucleosomes is all well and good, but how do cells gain access… Expand
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Review
2019
Review
2019
DNA methylation inhibitors have become the mainstay for treatment of certain haematological malignancies. In addition to their… Expand
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Review
2018
Review
2018
Recently, molecular hybridization paradigm became an interesting and smart way to defeat the multifaceted cancer disease by a… Expand
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Review
2018
Review
2018
Colorectal cancer (CRC) is one of the major health threats in developed countries. Changes in dietary components, such as more… Expand
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Review
2018
Review
2018
Abstract Zinc binding groups (ZBGs) play a crucial role in targeting histone deacetylase inhibitors (HDACIs) to the active site… Expand
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Review
2018
Review
2018
Alterations in the epigenome and metabolism affect molecular rewiring of cancer cells facilitating cancer development and… Expand
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