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Deacetylation

Deacetylation is the covalent chemical or post-translational biochemical removal of an acetyl group(s) from organic compounds.
National Institutes of Health

Related topics

Related topics

21 relations
DeacetylaseHDAC1 protein, humanHDAC4 protein, humanHDAC5 protein, human

Papers overview

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Highly Cited
2009
Highly Cited
2009
Combining Mass Spectrometry and Peptide Arrays to Profile the Specificities of Histone Deacetylases
This paper introduces the use of mass spectrometry to analyze peptide arrays for applications in profiling enzyme specificity… 
Highly Cited
2007
Highly Cited
2007
The use of chitosan as a flocculant in mammalian cell culture dramatically improves clarification throughput without adversely impacting monoclonal antibody recovery.
Highly Cited
2006
Highly Cited
2006
Unexpected deacetylation mechanism suggested by a density functional theory QM/MM study of histone-deacetylase-like protein.
To characterize the catalytic mechanism for zinc-dependent histone deacetylases (HDAC), we have carried out density functional… 
Highly Cited
2002
Highly Cited
2002
Histone deacetylation inhibits IL4 gene expression in T cells.
BACKGROUND Dysregulated expression of IL-4 has been linked with allergic diseases. IL-4 expression is controlled at the level of… 
2000
2000
The adenovirus‐2 E1B‐55K protein interacts with a mSin3A/histone deacetylase 1 complex
Highly Cited
1981
Highly Cited
1981
2,3-Dehydro-4-epi-N-acetylneuraminic acid; a neuraminidase inhibitor.
Highly Cited
1981
Highly Cited
1981
Glycophosphoceramides from plants. Purification and characterization of a novel tetrasaccharide derived from tobacco leaf glycolipids.
Highly Cited
1977
Highly Cited
1977
Metabolism of trichothecene mycotoxins. I. Microsomal deacetylation of T-2 toxin in animal tissues.
In an attempt to elucidate the active form of T-2 toxin, one of trichothecene mycotoxins in vivo, the metabolism in animal… 
1970
1970
Histone deacetylase from calf thymus.
Highly Cited
1969
Highly Cited
1969
N-hydroxy-2-fluorenylacetamide. Reaction of the carcinogen with guanosine, ribonucleic acid, deoxyribonucleic acid, and protein following enzymatic deacetylation or esterification.
Abstract Previous studies showed that the carcinogen N-hydroxy-2-fluorenylacetamide could react with RNA following enzymatic… 
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