HDAC4 protein, human

Known as: histone deacetylase 4, human, Histone Deacetylase 4, Histone Deacetylase A 
Histone deacetylase 4 (1084 aa, ~119 kDa) is encoded by the human HDAC4 gene. This protein plays a role in the regulation of cell differentiation and… (More)
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
  • 2013
Epileptic encephalopathies are a devastating group of severe childhood epilepsy disorders for which the cause is often unknown… (More)
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Highly Cited
2011
Highly Cited
2011
MicroRNAs (miRs) are emerging as prominent players in the regulation of many biological processes, including myogenic commitment… (More)
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Highly Cited
2011
Highly Cited
2011
Ovarian cancer frequently acquires resistance to platinum chemotherapy, representing a major challenge for improving patient… (More)
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Highly Cited
2008
Highly Cited
2008
The class II Histone deacetylase (HDAC), HDAC4, is expressed in a tissue-specific manner, and it represses differentiation of… (More)
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Highly Cited
2003
Highly Cited
2003
The class II histone deacetylases, HDAC4 and HDAC5, directly bind to and repress myogenic transcription factors of the myocyte… (More)
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Highly Cited
2002
Highly Cited
2002
Transcriptional repression mediated through histone deacetylation is a critical component of eukaryotic gene regulation. Here we… (More)
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Highly Cited
2000
Highly Cited
2000
Members of the myocyte enhancer factor-2 (MEF2) family of transcription factors associate with myogenic basic helix–loop–helix… (More)
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Highly Cited
1999
Highly Cited
1999
Gene expression is in part controlled by chromatin remodeling factors and the acetylation state of nucleosomal histones. The… (More)
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Highly Cited
1999
Highly Cited
1999
The acetylation state of histones can influence transcription. Acetylation, carried out by acetyltransferases such as CBP/p300… (More)
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Highly Cited
1999
Highly Cited
1999
Histone acetylation plays an important role in regulating chromatin structure and thus gene expression. Here we describe the… (More)
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