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Depsipeptide Antineoplastic Antibiotic

Known as: Depsipeptide 
A bicyclic peptide antibiotic with one or more amide bonds replaced by ester bonds. Depsipeptide antibiotics act as histone deacetylase inhibitors… Expand
National Institutes of Health

Papers overview

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2019
2019
A new cyclic depsipeptide (1) has been isolated from culture broth of Staphylococcus sp. (No. P-100826-4-6) derived from… Expand
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2007
2007
A depsipeptide is a chemical structure consisting of both ester and amide bonds. Quantum mechanics calculations have been… Expand
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Highly Cited
2006
Highly Cited
2006
Purpose: This phase II study was undertaken to assess objective response and toxicity of histone deacetylase inhibitor… Expand
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Highly Cited
2006
Highly Cited
2006
BACKGROUND Therapeutic options for renal cell cancer are inadequate. Depsipeptide is a histone deacetylase inhibitor with… Expand
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2006
2006
Nicotinamide N-methyltransferase (NNMT) catalyzes N-methylation of nicotinamide and other structural analogues. NNMT gene… Expand
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2005
2005
3061 Background: The histone deacetylase inhibitors (HDIs) are a class of differentiating agents undergoing clinical testing… Expand
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Highly Cited
1997
Highly Cited
1997
Transposon Tn1546 from Enterococcus faecium BM4147 encodes a histidine protein kinase (VanS) and a response regulator (VanR) that… Expand
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1972
1972
 
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