• Publications
  • Influence
Subclinical thyroid disease: scientific review and guidelines for diagnosis and management.
CONTEXT Patients with serum thyroid-stimulating hormone (TSH) levels outside the reference range and levels of free thyroxine (FT4) and triiodothyronine (T3) within the reference range are common inExpand
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Clinical Review: Hashimoto's thyroiditis and papillary thyroid carcinoma: is there a correlation?
CONTEXT The link between Hashimoto's thyroiditis (HT) and papillary thyroid cancer (PTC) has long been a topic of controversy. There are conflicting reports; some suggest that these two areExpand
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The aging thyroid. Thyroid deficiency in the Framingham Study.
In an unselected population of elderly (over age 60 years) men and women (the original cohort of the Framingham Study), the prevalence of thyroid deficiency, evidenced by a clearly elevated serumExpand
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Biologic effects of transdermal estradiol.
We conducted a dose-response study in 23 postmenopausal women to compare the physiologic effects of transdermal estradiol and oral conjugated equine estrogens. The doses studied were 25, 50, 100, andExpand
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Relation of gemfibrozil treatment and lipid levels with major coronary events: VA-HIT: a randomized controlled trial.
CONTEXT A low plasma level of high-density lipoprotein cholesterol (HDL-C) is a major risk factor for coronary heart disease (CHD). A secondary prevention study, the Veterans Affairs High-DensityExpand
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Ligands for peroxisome proliferator-activated receptor gamma inhibit growth and induce apoptosis of human papillary thyroid carcinoma cells.
Ligands for peroxisome proliferator-activated receptor gamma (PPARgamma) induce apoptosis and exert antiproliferative effects on several carcinoma cell lines. The present study investigates theExpand
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Physiological and pathological aspects of the effect of human chorionic gonadotropin on the thyroid.
  • J. Hershman
  • Medicine
  • Best practice & research. Clinical endocrinology…
  • 1 June 2004
Human chorionic gonadotropin (hCG) is a glycoprotein hormone that has structural similarity to TSH. At the time of the peak hCG levels in normal pregnancy, serum TSH levels fall and bear a mirrorExpand
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Characterization of tumor necrosis factor-alpha receptors in human and rat thyroid cells and regulation of the receptors by thyrotropin.
Administration of recombinant human tumor necrosis factor-alpha (TNF) to rats and mice produces a model of nonthyroid illness in which there is impairment of hypothalamic-pituitary thyroid function,Expand
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Thyroxine therapy in patients with severe nonthyroidal illnesses and low serum thyroxine concentration.
A randomized prospective study was done to assess the response of hypothyroxinemic patients with severe nonthyroidal illnesses to T4 therapy. Patients admitted to a medical intensive care unit whoExpand
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Thyrotropic action of human chorionic gonadotropin.
Hyperthyroidism or increased thyroid function has been reported in many patients with trophoblastic tumors. In these cases, greatly increased human chorionic gonadotropin (hCG) levels and suppressedExpand
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