Homophymine A, an anti-HIV cyclodepsipeptide from the sponge Homophymia sp.
- A. Zampella, V. Sepe, A. Ahond
- Chemistry, BiologyJournal of Organic Chemistry
- 19 June 2008
A new anti-HIV cyclodepsipeptide was isolated from a New Caledonian collection of the marine sponge Homophymia sp.
Homophymines B-E and A1-E1, a family of bioactive cyclodepsipeptides from the sponge Homophymia sp.
- A. Zampella, V. Sepe, A. Ahond
- Chemistry, BiologyOrganic and biomolecular chemistry
- 16 September 2009
Nine new cyclodepsipeptides, homophymines B-E (2-5) and A1-E1 (1a-5a), were isolated from the polar extracts of the sponge Homophymia sp, featuring new polyketide-derived end groups, determined by interpretation of NMR and MS data.
New bioactive halenaquinone derivatives from South Pacific marine sponges of the genus Xestospongia.
- A. Longeon, B. Copp, M. Bourguet-Kondracki
- Chemistry, BiologyBioorganic & Medicinal Chemistry
- 15 August 2010
Metabolites from the Sponge-Associated Bacterium Pseudomonas Species
- V. Bultel‐Poncé, J. Bergé, C. Debitus, J. Nicolas, M. Guyot
- Chemistry, EngineeringMarine Biotechnology
- 1 July 1999
Abstract: Quinolones and a phosphatidyl glyceride were isolated from the sponge-associated bacterial strain Pseudomonas sp. Structures were elucidated by spectroscopic analysis and chemical…
Alisiaquinones and alisiaquinol, dual inhibitors of Plasmodium falciparum enzyme targets from a New Caledonian deep water sponge.
- D. Desoubzdanne, L. Marcourt, C. Debitus
- ChemistryJournal of Natural Products
- 31 May 2008
Four new meroterpenes were isolated from a New Caledonian deep water sponge and showed unusual substitution on a tetrahydrofuran junction, and displayed micromolar range activity on two enzymatic targets of importance for the control of malaria and a competitive selectivity index on the different plasmodial strains.
New sesquiterpene derivatives from the sponge Dysidea species with a selective inhibitor profile against human phospholipase A2 and other leukocyte functions.
- C. Giannini, C. Debitus, M. V. D’Auria
- Chemistry, BiologyJournal of Natural Products
- 28 April 2001
Bolinaquinone (1), dysidine (4), and a 1:1 mixture of dysidenones A and B (2, 3) significantly inhibited human synovial phospholipase A2 (PLA2) at 10 microM, which exerts a higher potency and selectivity toward this enzyme than the reference inhibitor manoalide.
Halipeptins A and B: two novel potent anti-inflammatory cyclic depsipeptides from the Vanuatu marine sponge Haliclona species.
- A. Randazzo, G. Bifulco, L. Gomez‐Paloma
- Chemistry, BiologyJournal of the American Chemical Society
- 13 October 2001
Two new metabolites, named halipeptins A and B, have been isolated from the marine sponge Haliclona sp. Their structures were determined by extensive use of one- and two-dimensional NMR experiments,…
Theonellasterols and conicasterols from Theonella swinhoei. Novel marine natural ligands for human nuclear receptors.
- S. De Marino, Raffaella Ummarino, A. Zampella
- Biology, ChemistryJournal of Medicinal Chemistry
- 5 April 2011
Pharmacological and structure-activity relationship analysis demonstrate that these natural polyhydroxylated steroids are potent ligands of human nuclear pregnane receptor (PXR) and modulator of farnesoid-X-receptor (FXR).
Bioactive Indole Derivatives from the South Pacific Marine Sponges Rhopaloeides odorabile and Hyrtios sp.
- A. Longeon, B. Copp, M. Bourguet-Kondracki
- ChemistryMarine Drugs
- 24 May 2011
Indole derivatives including bromoindoles have been isolated from the South Pacific marine sponges Rhopaloeides odorabile and Hyrtios sp. Their structures were established through analysis of mass…
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