Selegiline

Known as: L-Deprenyl, (-)-selegiline, Selegiline [Chemical/Ingredient] 
A selective, irreversible inhibitor of Type B monoamine oxidase. It is used in newly diagnosed patients with Parkinson's disease. It may slow… (More)
National Institutes of Health

Papers overview

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Highly Cited
2017
Highly Cited
2017
18F-THK5351 is a quinoline-derived tau imaging agent with high affinity to paired helical filaments (PHF). However, high levels… (More)
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Highly Cited
2006
Highly Cited
2006
OBJECTIVE To study the long-term effects of selegiline in monotherapy and in combination with levodopa in the early phase of… (More)
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Highly Cited
2002
Highly Cited
2002
Deprenyl (selegiline) delays the need for levodopa therapy in patients with early Parkinson's disease, but the long-term benefits… (More)
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Review
2002
Review
2002
Selegiline, a selective inhibitor of monoamine oxidase-B (MAO-B), was one of the first adjunct therapies in clinical neurology. A… (More)
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Review
2001
Review
2001
Free radicals and other so-called 'reactive species' are constantly produced in the brain in vivo. Some arise by 'accidents of… (More)
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Highly Cited
2000
Highly Cited
2000
The neuropathology of Parkinson's disease is reflected in experimental animals treated with the selective nigrostriatal… (More)
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Highly Cited
1997
Highly Cited
1997
BACKGROUND There is evidence that medications or vitamins that increase the levels of brain catecholamines and protect against… (More)
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Review
1996
Review
1996
The acetylenic selective monoamine oxidase (MAO) type B suicide inhibitor selegiline (previously called L-deprenyl) has proved to… (More)
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Review
1996
Review
1996
Current concepts of the pathogenesis of Parkinson's disease (PD) center on the formation of reactive oxygen species and the onset… (More)
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Highly Cited
1995
Highly Cited
1995
The enzymes of mitochondrial respiratory chain, NADH dehydrogenase (complex I) and cytochrome c oxidase (complex IV), were… (More)
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