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Deprenyl

National Institutes of Health

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Broader (4)

Antiparkinson AgentsMonoamine Oxidase InhibitorsPhenethylaminesSelegiline
Selegiline, (R,S)-Isomer

Papers overview

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Highly Cited
2014
Highly Cited
2014
Cerebrospinal fluid α-synuclein predicts cognitive decline in Parkinson disease progression in the DATATOP cohort.
Highly Cited
2005
Highly Cited
2005
Neuroprotection of MPTP-induced toxicity in zebrafish dopaminergic neurons.
Highly Cited
2001
Highly Cited
2001
Dieldrin-induced oxidative stress and neurochemical changes contribute to apoptopic cell death in dopaminergic cells.
Highly Cited
1996
Highly Cited
1996
Impact of deprenyl and tocopherol treatment on Parkinson's disease in DATATOP patients requiring levodopa
The Deprenyl and Tocopherol Antioxidant Therapy of Parkinsonism (DATATOP) trial was designed to test outcomes from treatment with… 
Highly Cited
1995
Highly Cited
1995
The effect of deprenyl and levodopa on the progression of Parkinson's disease
We have performed a 14‐month, prospective, randomized, double‐blind, placebo‐controlled study to evaluate the effect of deprenyl… 
Highly Cited
1995
Highly Cited
1995
Selective reduction of radiotracer trapping by deuterium substitution: comparison of carbon-11-L-deprenyl and carbon-11-deprenyl-D2 for MAO B mapping.
UNLABELLED Recent human PET studies with the monoamine oxidase B (MAO B) tracer [11C]L-deprenyl show that the rapid rate of… 
Highly Cited
1986
Highly Cited
1986
Monoamine Oxidase Activity and Monoamine Metabolism in Brains of Parkinsonian Patients Treated with l‐Deprenyl
Abstract: Monoamine oxidase (MAO) type A and type B were measured using kynuramine, 3,4‐dihydroxyphenyl‐ethylamine (dopamine, DA… 
Highly Cited
1984
Highly Cited
1984
Metabolism of the neurotoxic tertiary amine, MPTP, by brain monoamine oxidase.
Highly Cited
1984
Highly Cited
1984
Oxidation of the neurotoxic amine 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) by monoamine oxidases A and B and suicide inactivation of the enzymes by MPTP.
Highly Cited
1978
Highly Cited
1978
A benzylamine oxidase distinct from monoamine oxidase B--widespread distribution in man and rat.
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