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It is revealed that norepinephrine and dopamine are specifically localized in complex systems of neurons in the brain, a finding which lends support to the hypothesis that both amines may be neurotransmitters in the central nervous system. Expand
Spontaneous and Evoked Activity of Substantia Nigra Pars Reticulata Neurons during High-Frequency Stimulation of the Subthalamic Nucleus
The present data indicate that STN high-frequency stimulation influences the activity of SNR cells through activation of their excitatory and inhibitory synaptic afferent pathways as well as antidromic activation of the projection neurons. Expand
Importance of the Noradrenaline–Dopamine Coupling in the Locomotor Activating Effects of d-Amphetamine
Results suggest that locomotor activating effects of d-amphetamine are caused by the stimulation of cortical α1-adrenergic receptors by noradrenaline, which increases the release of a functional part of subcortical DA. Expand
Astrocytes protect neurons from hydrogen peroxide toxicity
Astrocytes could delay neuronal death in pathological situations in which H2O2 has been, at least partially, demonstrated to be involved, according to reports on neurons particularly sensitive to hydrogen peroxide. Expand
Dendritic release of dopamine in the substantia nigra
Dopamine can be released in the substantia nigra from the dendrites of nigrostriatal dopaminergic neurones, to be involved there in the self-regulation of the dopaminergic cells, to control theExpand
Pyruvate Protects Neurons against Hydrogen Peroxide-Induced Toxicity
Results indicate that pyruvate efficiently protects neurons against both exogenous and endogenous H2O2, and its low toxicity and its capacity to cross the blood–brain barrier open a new therapeutic perspective in brain pathologies in which H2 O2 is involved. Expand
Influence of the hippocampus on interneurons of the rat prefrontal cortex
The hippocampus exerts a direct excitatory influence on PFC interneurons and is thus capable of feedforward inhibition of pyramidal cells, resulting in synchronization of a specific subset of PFC neurons with hippocampal activity. Expand
Mechanism Involved in Initiation and Propagation of Receptor-Induced Intercellular Calcium Signaling in Cultured Rat Astrocytes
In rat astrocytes, initiation and propagation of calcium waves involve a sequence of intra- and intercellular steps in which phospholipase C, inositol trisphosphate, internal calcium stores, and gap junction channels play a critical role, and the identification of these different events allows us to determine several targets at which the level of long-range signaling in astroCytes may be controlled. Expand
Spinal tuberculosis in adults. A study of 103 cases in a developed country, 1980-1994.
The data suggest that SPwD may now be the most common pattern of spinal TB in foreign-born subjects in industrialized countries, and the reasons for this remain to be elucidated. Expand
Selective activation of the mesocortical DA system by stress
The results suggest that the mesocortical DA system is selectively activated by this stress induced by electric foot shocks, and the antipsychotic effects of neuroleptics are in part related to the blockade of postsynaptic DA receptors localised in areas innervated by the mesolimbic and mesocORTical DA systems. Expand