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Epidermal Growth Factor Receptor

Known as: Transforming Growth Factor alpha Receptor, Receptor, TGF alpha, Receptor, ErbB-1 
A cell surface receptor involved in regulation of cell growth and differentiation. It is specific for EPIDERMAL GROWTH FACTOR and EGF-related… 
National Institutes of Health

Related topics

Related topics

27 relations
BIBX 1382EGFR geneEGFR wt AlleleERBB2 gene

Narrower (5)

EGFR protein, Anopheles gambiaeEGFR protein, humanEgfr protein, Drosophilaepidermal growth factor receptor VIII

Broader (2)

Growth Factor ReceptorsReceptor Protein-Tyrosine Kinases

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2008
Highly Cited
2008
TACE/ADAM-17: A Component of the Epidermal Growth Factor Receptor Axis and a Promising Therapeutic Target in Colorectal Cancer
Purpose: Activation of the epidermal growth factor receptor (EGFR) requires cell surface cleavage of EGFR ligands, uptake of… 
Highly Cited
2005
Highly Cited
2005
Antivascular Therapy for Orthotopic Human Ovarian Carcinoma through Blockade of the Vascular Endothelial Growth Factor and Epidermal Growth Factor Receptors
Purpose: We determined whether the administration of the tyrosine kinase inhibitor, AEE788, which targets the epidermal growth… 
Highly Cited
2005
Highly Cited
2005
A basic peptide within the juxtamembrane region is required for EGF receptor dimerization.
Highly Cited
2001
Highly Cited
2001
C225 antiepidermal growth factor receptor antibody enhances tumor radiocurability.
Highly Cited
1999
Highly Cited
1999
ebi regulates epidermal growth factor receptor signaling pathways in Drosophila.
ebi regulates the epidermal growth factor receptor (EGFR) signaling pathway at multiple steps in Drosophila development… 
Highly Cited
1998
Highly Cited
1998
A chimeric fusion protein containing transforming growth factor-α mediates gene transfer via binding to the EGF receptor
Fusion proteins engineered to incorporate distinct functions which co-operate in mediating the cell-type specific uptake and… 
Highly Cited
1996
Highly Cited
1996
The Interaction of an Epidermal Growth Factor/Transforming Growth Factor α Tail Chimera with the Human Epidermal Growth Factor Receptor Reveals Unexpected Complexities*
It has been assumed that substitution of homologous regions of transforming growth factor α (TGF-α) into epidermal growth factor… 
Highly Cited
1992
Highly Cited
1992
Signal transmission by epidermal growth factor receptor: coincidence of activation and dimerization.
Dimerization of epidermal growth factor receptor dissolved in a solution of nonionic detergent was followed with a resolution of… 
Highly Cited
1986
Highly Cited
1986
Alternative 5′ exons and tissue-specific expression of the Drosophila EGF receptor homolog transcripts
Highly Cited
1983
Highly Cited
1983
Identification and characterization of the avian erythroblastosis virus erbB gene product as a membrane glycoprotein
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