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Epidermal Growth Factor Receptor

Known as: Transforming Growth Factor alpha Receptor, Receptor, TGF alpha, Receptor, ErbB-1 
A cell surface receptor involved in regulation of cell growth and differentiation. It is specific for EPIDERMAL GROWTH FACTOR and EGF-related… Expand
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
Lung cancer with epidermal growth factor receptor (EGFR)-activating mutations responds favorably to the EGFR tyrosine kinase… Expand
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Review
2006
Review
2006
The epidermal growth factor receptor (EGFR) belongs to the ErbB family of receptor tyrosine kinases (RTK). These trans-membrane… Expand
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Highly Cited
2006
Highly Cited
2006
The mechanism by which the epidermal growth factor receptor (EGFR) is activated upon dimerization has eluded definition. We find… Expand
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Review
2006
Review
2006
Epidermal growth factor receptor (EGFR) is overexpressed in several epithelial malignancies, including head and neck squamous… Expand
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Highly Cited
2005
Highly Cited
2005
The epidermal growth factor receptor (EGFR) signaling pathway is one of the most important pathways that regulate growth… Expand
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Highly Cited
2005
Highly Cited
2005
Recent structural studies of epidermal growth factor receptor (EGFR) family extracellular regions have identified an unexpected… Expand
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Highly Cited
2002
Highly Cited
2002
The crystal structure of the kinase domain from the epidermal growth factor receptor (EGFRK) including forty amino acids from the… Expand
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Highly Cited
1995
Highly Cited
1995
The epidermal growth factor receptor (EGFR) is a protein tyrosine kinase expressed on many types of tumor cells, including breast… Expand
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Highly Cited
1992
Highly Cited
1992
The epidermal growth factor receptor (EGFR) gene is amplified in 40% of malignant gliomas, and the amplified genes are frequently… Expand
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Highly Cited
1984
Highly Cited
1984
The complete 1,210-amino acid sequence of the human epidermal growth factor (EGF) receptor precursor, deduced from cDNA clones… Expand
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