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Epidermal Growth Factor Receptor
Known as:
Transforming Growth Factor alpha Receptor
, Receptor, TGF alpha
, Receptor, ErbB-1
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A cell surface receptor involved in regulation of cell growth and differentiation. It is specific for EPIDERMAL GROWTH FACTOR and EGF-related…
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National Institutes of Health
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Related topics
Related topics
27 relations
BIBX 1382
EGFR gene
EGFR wt Allele
ERBB2 gene
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Narrower (5)
EGFR protein, Anopheles gambiae
EGFR protein, human
Egfr protein, Drosophila
epidermal growth factor receptor VIII
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Broader (2)
Growth Factor Receptors
Receptor Protein-Tyrosine Kinases
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2008
Highly Cited
2008
TACE/ADAM-17: A Component of the Epidermal Growth Factor Receptor Axis and a Promising Therapeutic Target in Colorectal Cancer
N. Merchant
,
Igor V. Voskresensky
,
+8 authors
R. Coffey
Clinical Cancer Research
2008
Corpus ID: 16640637
Purpose: Activation of the epidermal growth factor receptor (EGFR) requires cell surface cleavage of EGFR ligands, uptake of…
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Highly Cited
2005
Highly Cited
2005
Antivascular Therapy for Orthotopic Human Ovarian Carcinoma through Blockade of the Vascular Endothelial Growth Factor and Epidermal Growth Factor Receptors
P. Thaker
,
S. Yazıcı
,
+6 authors
A. Sood
Clinical Cancer Research
2005
Corpus ID: 10914228
Purpose: We determined whether the administration of the tyrosine kinase inhibitor, AEE788, which targets the epidermal growth…
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Highly Cited
2005
Highly Cited
2005
A basic peptide within the juxtamembrane region is required for EGF receptor dimerization.
S. Aifa
,
J. Aydin
,
G. Nordvall
,
I. Lundström
,
S. Svensson
,
O. Hermanson
Experimental Cell Research
2005
Corpus ID: 12942739
Highly Cited
2001
Highly Cited
2001
C225 antiepidermal growth factor receptor antibody enhances tumor radiocurability.
S. Nasu
,
K. Ang
,
Z. Fan
,
L. Milas
International Journal of Radiation Oncology…
2001
Corpus ID: 28940075
Highly Cited
1999
Highly Cited
1999
ebi regulates epidermal growth factor receptor signaling pathways in Drosophila.
Xinzhong Dong
,
Leo Tsuda
,
+4 authors
S. Zipursky
Genes & Development
1999
Corpus ID: 8435525
ebi regulates the epidermal growth factor receptor (EGFR) signaling pathway at multiple steps in Drosophila development…
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Highly Cited
1998
Highly Cited
1998
A chimeric fusion protein containing transforming growth factor-α mediates gene transfer via binding to the EGF receptor
J. Fominaya
,
C. Uherek
,
W. Wels
Gene Therapy
1998
Corpus ID: 6475252
Fusion proteins engineered to incorporate distinct functions which co-operate in mediating the cell-type specific uptake and…
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Highly Cited
1996
Highly Cited
1996
The Interaction of an Epidermal Growth Factor/Transforming Growth Factor α Tail Chimera with the Human Epidermal Growth Factor Receptor Reveals Unexpected Complexities*
S. Puddicombe
,
L. Wood
,
S. G. Chamberlin
,
D. Davies
Journal of Biological Chemistry
1996
Corpus ID: 37140269
It has been assumed that substitution of homologous regions of transforming growth factor α (TGF-α) into epidermal growth factor…
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Highly Cited
1992
Highly Cited
1992
Signal transmission by epidermal growth factor receptor: coincidence of activation and dimerization.
Francisco Canals
Biochemistry
1992
Corpus ID: 33096404
Dimerization of epidermal growth factor receptor dissolved in a solution of nonionic detergent was followed with a resolution of…
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Highly Cited
1986
Highly Cited
1986
Alternative 5′ exons and tissue-specific expression of the Drosophila EGF receptor homolog transcripts
E. Schejter
,
D. Segal
,
L. Glazer
,
B. Shilo
Cell
1986
Corpus ID: 28896851
Highly Cited
1983
Highly Cited
1983
Identification and characterization of the avian erythroblastosis virus erbB gene product as a membrane glycoprotein
M. Hayman
,
G. Ramsay
,
K. Savin
,
G. Kitchener
,
T. Graf
,
H. Beug
Cell
1983
Corpus ID: 23856625
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