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EGFR protein, human

Known as: Cell Growth Inhibiting Protein 40, ErbB1, Cell Proliferation-Inducing Protein 61 
The protein found on the surface of some cells and to which epidermal growth factor binds, causing the cells to divide. It is found at abnormally… Expand
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
BACKGROUND Patients with non-small-cell lung cancer harbouring mutations in the epidermal growth factor receptor (EGFR) gene… Expand
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Highly Cited
2010
Highly Cited
2010
PURPOSE The risk of local and regional relapse associated with each breast cancer molecular subtype was determined in a large… Expand
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Highly Cited
2006
Highly Cited
2006
The mechanism by which the epidermal growth factor receptor (EGFR) is activated upon dimerization has eluded definition. We find… Expand
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Highly Cited
2004
Highly Cited
2004
BACKGROUND Most patients with non-small-cell lung cancer have no response to the tyrosine kinase inhibitor gefitinib, which… Expand
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Review
2004
Review
2004
  • R. Herbst
  • International journal of radiation oncology…
  • 2004
  • Corpus ID: 25970117
The epidermal growth factor receptor (EGFR) is a transmembrane glycoprotein that constitutes one of four members of the erbB… Expand
Highly Cited
2003
Highly Cited
2003
CONTEXT More persons in the United States die from non-small cell lung cancer (NSCLC) than from breast, colorectal, and prostate… Expand
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Highly Cited
2001
Highly Cited
2001
PURPOSE Expression of ErbB-1 and ErbB-2 (epidermal growth factor receptor and HER2/neu) in breast cancer may cause tamoxifen… Expand
Review
2000
Review
2000
Human carcinomas frequently express high levels of receptors in the EGF receptor family, and overexpression of at least two of… Expand
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Highly Cited
1996
Highly Cited
1996
TRANSDUCTION of a mitogenic signal from the cell membrane to the nucleus involves the adapter proteins SHC and Grb2, which… Expand
Highly Cited
1985
Highly Cited
1985
Epidermal growth factor (EGF), through interaction with specific cell surface receptors, generates a pleiotropic response that… Expand