EGFR protein, human

Known as: Cell Growth Inhibiting Protein 40, ErbB1, Cell Proliferation-Inducing Protein 61 
The protein found on the surface of some cells and to which epidermal growth factor binds, causing the cells to divide. It is found at abnormally… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1985-2017
05010015019852017

Papers overview

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Highly Cited
2012
Highly Cited
2012
UNLABELLED Activation of the epidermal growth factor receptor (EGFR) in glioblastoma (GBM) occurs through mutations or deletions… (More)
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Highly Cited
2010
Highly Cited
2010
BACKGROUND First-line chemotherapy for advanced non-small-cell lung cancer (NSCLC) is usually limited to four to six cycles… (More)
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Highly Cited
2010
Highly Cited
2010
PURPOSE Preclinical data have demonstrated that BIBW 2992 is a potent irreversible inhibitor of ErbB1 (EGFR/HER1) and mutated… (More)
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Highly Cited
2003
Highly Cited
2003
ErbB2 does not bind ligand, yet appears to be the major signaling partner for other ErbB receptors by forming heteromeric… (More)
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Highly Cited
2003
Highly Cited
2003
PURPOSE ZD1839 is a tyrosine kinase inhibitor of the epidermal growth factor receptor (EGFR) that has shown clinical activity… (More)
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Highly Cited
2002
Highly Cited
2002
Prostaglandins (PGs), bioactive lipid molecules produced by cyclooxygenase enzymes (COX-1 and COX-2), have diverse biological… (More)
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Highly Cited
2001
Highly Cited
2001
Both ErbB1 and ErbB2 are overexpressed or amplified in breast tumours. To examine the effects of activating ErbB receptors in a… (More)
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Highly Cited
2001
Highly Cited
2001
ErbB receptors are a family of ligand-activated tyrosine kinases that play a central role in proliferation, differentiation, and… (More)
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Highly Cited
2001
Highly Cited
2001
It is well established that ErbB1 and ErbB2 can cooperate in mammary epithelial cell transformation. Therefore, to understand how… (More)
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Highly Cited
1985
Highly Cited
1985
From a human genomic library, we obtained six v-erbB-related DNA clones. A DNA probe prepared from one of the clones, lambda 107… (More)
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