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Cardiac Hypertrophy Pathway

Known as: Role of EGF Receptor Transactivation by GPCRs in Cardiac Hypertrophy 
One of responses to increased blood pressure is cardiac hypertrophy through increased size of ventricular myocardial cells leading to increased… 
National Institutes of Health

Related topics

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32 relations
ADAM12 protein, humanADAM12 wt AlleleAGT wt AlleleAGTR2 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2019
Highly Cited
2019
Direct visualization of cAMP signaling in primary cilia reveals up-regulation of ciliary GPCR activity following Hedgehog activation
Significance The primary cilium, a small organelle essential to normal development, has recently been thrust into the limelight… 
2019
2019
DAKB-GPCRs: An Integrated Computational Platform for Drug Abuse Related GPCRs
Drug abuse (DA) or drug addiction is a complicated brain disorder which is commonly considered as neurobiological impairments… 
Review
2017
Review
2017
The effects of RAMPs upon cell signalling
Review
2016
Review
2016
Optogenetic user's guide to Opto-GPCRs.
Optogenetics has taken biomedical research by storm. The power and precision at which light-gated ion channels control cellular… 
Review
2015
Review
2015
Bone and skeletal muscle: Key players in mechanotransduction and potential overlapping mechanisms.
2015
2015
Extracellular Surface Residues of the α1B-Adrenoceptor Critical for G Protein–Coupled Receptor Function
Ligand binding and conformational changes that accompany signaling from G protein–coupled receptors (GPCRs) have mostly focused… 
Review
2013
Review
2013
Unlocking the secrets of the gatekeeper: methods for stabilizing and crystallizing GPCRs.
2011
2011
Ouabain facilitates cardiac differentiation of mouse embryonic stem cells through ERK1/2 pathway
Aim:To investigate the effects of the cardiotonic steroid, ouabain, on cardiac differentiation of murine embyronic stem cells… 
Review
2010
Review
2010
Nonpeptide ligands for peptidergic G protein-coupled receptors.
Neuropeptides play essential roles in many physiological systems in vertebrates and invertebrates. Peptides per se are difficult… 
Review
2008
Review
2008
High throughput screening for orphan and liganded GPCRs.
GPCRs had significant representation in the drug discovery portfolios of most major commercial drug discovery organizations for… 
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