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Cardiac Hypertrophy Pathway

Known as: Role of EGF Receptor Transactivation by GPCRs in Cardiac Hypertrophy 
One of responses to increased blood pressure is cardiac hypertrophy through increased size of ventricular myocardial cells leading to increased… 
National Institutes of Health

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32 relations
ADAM12 protein, humanADAM12 wt AlleleAGT wt AlleleAGTR2 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Conserved 2nd Residue of Helix 8 of GPCR May Confer the Subclass-Characteristic and Distinct Roles through a Rapid Initial Interaction with Specific G Proteins
To obtain a systematic view of the helix-8-second residue responsible for G protein-coupled receptor (GPCR)–G protein initial… 
Review
2019
Review
2019
Multiscale simulations on human Frizzled and Taste2 GPCRs.
Review
2017
Review
2017
Conceptual Progress for the Improvements in the Selectivity and Efficacy of G Protein-Coupled Receptor Therapeutics: An Overview
membrane proteins that transduce exterior stimuli into intracellular signals. GPCRs are also known as seven-transmembrane domain… 
2013
2013
Estudio de la funcionalidad de GPCRs mediante el uso de herramientas biológicas y químicas: aplicación a los receptores 5-HT2A y 5- HT7 de serotonina
En la presente tesis doctoral, empleando herramientas biologicas disenadas ad-hoc, tales como receptores deficientes en union de… 
2011
2011
Ouabain facilitates cardiac differentiation of mouse embryonic stem cells through ERK1/2 pathway
Aim:To investigate the effects of the cardiotonic steroid, ouabain, on cardiac differentiation of murine embyronic stem cells… 
Review
2010
Review
2010
Nonpeptide ligands for peptidergic G protein-coupled receptors.
Neuropeptides play essential roles in many physiological systems in vertebrates and invertebrates. Peptides per se are difficult… 
2009
2009
El interactoma de la quinasa GRK2 y sus implicaciones fisiopatológicas
Las quinasas de receptores acoplados a proteinas G (GRKs) representan un importante punto de convergencia de diferentes rutas de… 
Review
2008
Review
2008
High throughput screening for orphan and liganded GPCRs.
GPCRs had significant representation in the drug discovery portfolios of most major commercial drug discovery organizations for… 
Review
2007
Review
2007
[GPCRs heterodimerization: a new way towards the discovery of function for the orphan receptors?].
G protein-coupled receptors (GPCRs), also called seven transmembrane domain (7TM) proteins, represent the largest family of cell… 
Review
2002
Review
2002
Dissecting the molecular mechanisms of olfaction in a malaria-vector mosquito
Human malaria is widely endemic in tropical and subtropical regions of the world, where ca. 1.5 billion people are at risk, ca… 
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