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Growth Factor Receptors
Known as:
Growth Factor, Receptor
, Growth Factors Receptors
, Growth Factor Receptor
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A class of cell surface proteins that bind to extracellular polypeptide molecules triggering intracellular signaling pathways that activate various…
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National Institutes of Health
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Related topics
Related topics
48 relations
Activin Receptor
Cell Proliferation Regulatory Process
EGFR protein, human
ERBB2 Gene Product
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Narrower (7)
Epidermal Growth Factor Receptor
Insulin Receptor
VEGF Trap R1R2 protein
agrin receptor
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Broader (2)
Receptors, Cell Surface
receptor
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2014
Review
2014
Recommendations for human epidermal growth factor receptor 2 testing in breast cancer: American Society of Clinical Oncology/College of American Pathologists clinical practice guideline update.
A. Wolff
,
M. Hammond
,
+17 authors
D. Hayes
Archives of Pathology & Laboratory Medicine
2014
Corpus ID: 10032496
PURPOSE To update the American Society of Clinical Oncology (ASCO)/College of American Pathologists (CAP) guideline…
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Highly Cited
2010
Highly Cited
2010
Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): a phase 3, open-label, randomised…
Y. Bang
,
E. Cutsem
,
+13 authors
Yoon-Koo Kang
The Lancet
2010
Corpus ID: 8825706
Review
2007
Review
2007
Epidermal growth factor receptor mutations in lung cancer
Sreenath V. Sharma
,
D. Bell
,
J. Settleman
,
D. Haber
Nature Reviews. Cancer
2007
Corpus ID: 3087406
The development and clinical application of inhibitors that target the epidermal growth factor receptor (EGFR) provide important…
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Review
2006
Review
2006
American Society of Clinical Oncology/College of American Pathologists guideline recommendations for human epidermal growth factor receptor 2 testing in breast cancer.
A. Wolff
,
M. Hammond
,
+20 authors
D. Hayes
Journal of Clinical Oncology
2006
Corpus ID: 16407713
PURPOSE To develop a guideline to improve the accuracy of human epidermal growth factor receptor 2 (HER2) testing in invasive…
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Highly Cited
2006
Highly Cited
2006
Clinical and biological features associated with epidermal growth factor receptor gene mutations in lung cancers.
H. Shigematsu
,
Li Lin
,
+13 authors
A. Gazdar
Journal of the National Cancer Institute
2006
Corpus ID: 17226491
BACKGROUND Mutations in the tyrosine kinase (TK) domain of the epidermal growth factor receptor (EGFR) gene in lung cancers are…
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Highly Cited
2004
Highly Cited
2004
Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib.
T. Lynch
,
D. Bell
,
+11 authors
D. Haber
New England Journal of Medicine
2004
Corpus ID: 27937216
BACKGROUND Most patients with non-small-cell lung cancer have no response to the tyrosine kinase inhibitor gefitinib, which…
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Highly Cited
2003
Highly Cited
2003
In vivo antitumor activity of SU11248, a novel tyrosine kinase inhibitor targeting vascular endothelial growth factor and platelet-derived growth factor receptors: determination of a pharmacokinetic…
D. Mendel
,
A. Laird
,
+20 authors
J. Cherrington
Clinical Cancer Research
2003
Corpus ID: 1801681
One challenging aspect in the clinical development of molecularly targeted therapies, which represent a new and promising…
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Highly Cited
1991
Highly Cited
1991
Identification of the hepatocyte growth factor receptor as the c-met proto-oncogene product.
D. Bottaro
,
J. Rubin
,
+4 authors
S. Aaronson
Science
1991
Corpus ID: 31222494
Hepatocyte growth factor (HGF) is a plasminogen-like protein thought to be a humoral mediator of liver regeneration. A 145…
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Highly Cited
1984
Highly Cited
1984
Close similarity of epidermal growth factor receptor and v-erb-B oncogene protein sequences
J. Downward
,
Y. Yarden
,
+6 authors
M. Waterfield
Nature
1984
Corpus ID: 12253530
Each of six peptides derived from the human epidermal growth factor (EGF) receptor very closely matches a part of the deduced…
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Highly Cited
1984
Highly Cited
1984
Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells
A. Ullrich
,
L. Coussens
,
+12 authors
P. Seeburg
Nature
1984
Corpus ID: 4261582
The complete 1,210-amino acid sequence of the human epidermal growth factor (EGF) receptor precursor, deduced from cDNA clones…
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