Growth Factor Receptors

Known as: Growth Factor, Receptor, Growth Factors Receptors, Growth Factor Receptor 
A class of cell surface proteins that bind to extracellular polypeptide molecules triggering intracellular signaling pathways that activate various… (More)

Topic mentions per year

Topic mentions per year

1954-2017
010002000300019542016

Papers overview

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Review
2016
Review
2016
Patients with advanced melanoma have traditionally had very poor prognosis. However, since 2011 better understanding of the… (More)
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Review
2016
Review
2016
The tyrosine kinase inhibitors (TKI) of the epidermal growth factor receptor (EGFR) are becoming the first line of therapy for… (More)
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Review
2016
Review
2016
Mutation of the KRAS oncogene in pancreatic cancer is responsible for permanent activation of the P21 RAS protein and the cascade… (More)
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Review
2015
Review
2015
Head and neck cancers, which affect 650,000 people and cause 350,000 deaths per year, is the sixth leading cancer by cancer… (More)
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Highly Cited
2006
Highly Cited
2006
PURPOSE Renal cell carcinoma (RCC) is characterized by loss of von Hippel Lindau tumor suppressor gene activity, resulting in… (More)
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Highly Cited
2005
Highly Cited
2005
BACKGROUND Gefitinib is a selective inhibitor of the epidermal growth factor (EGFR) tyrosine kinase, which is overexpressed in… (More)
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Highly Cited
2004
Highly Cited
2004
BACKGROUND Most patients with non-small-cell lung cancer have no response to the tyrosine kinase inhibitor gefitinib, which… (More)
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Highly Cited
2003
Highly Cited
2003
One challenging aspect in the clinical development of molecularly targeted therapies, which represent a new and promising… (More)
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Highly Cited
2003
Highly Cited
2003
CONTEXT More persons in the United States die from non-small cell lung cancer (NSCLC) than from breast, colorectal, and prostate… (More)
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Highly Cited
1991
Highly Cited
1991
Hepatocyte growth factor (HGF) is a plasminogen-like protein thought to be a humoral mediator of liver regeneration. A 145… (More)
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