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Receptor Protein-Tyrosine Kinases

Known as: Receptor Protein Tyrosine Kinases, Tyrosine Kinase Growth Factor Receptor, Protein-Tyrosine Kinase Receptors 
A class of membrane receptors that contain protein tyrosine kinase activity. This enzymatic activity is integral to the function of the receptor as a… 
National Institutes of Health

Related topics

Related topics

50 relations
Cell Differentiation processCell ProliferationEnzyme GeneImatinib mesylate

Narrower (21)

DRL protein, DrosophilaEPHA3 protein, humanEphA3 ReceptorEphrin Receptor EphB1

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2003
Highly Cited
2003
CEP-7055: a novel, orally active pan inhibitor of vascular endothelial growth factor receptor tyrosine kinases with potent antiangiogenic activity and antitumor efficacy in preclinical models.
Inhibition of the vascular endothelial growth factor VEGF-VEGF receptor (VEGF-R) kinase axes in the tumor angiogenic cascade is a… 
Highly Cited
1996
Highly Cited
1996
Daughter of Sevenless Is a Substrate of the Phosphotyrosine Phosphatase Corkscrew and Functions during Sevenless Signaling
Highly Cited
1995
Highly Cited
1995
Control of neuronal pathway selection by a Drosophila receptor protein-tyrosine kinase family member
DURING development, neurons are capable of selecting specific pathways that lead them to their appropriate target areas. A… 
Highly Cited
1994
Highly Cited
1994
Binding of beta gamma subunits of heterotrimeric G proteins to the PH domain of Bruton tyrosine kinase.
Bruton tyrosine kinase (Btk) has been implicated as the defective gene in both human and murine B-cell deficiencies. The… 
Review
1994
Review
1994
Receptor tyrosine kinases and their targets.
Highly Cited
1994
Highly Cited
1994
Insulin receptor substrate 1 mediates the stimulatory effect of insulin on GLUT4 translocation in transfected rat adipose cells.
Review
1992
Review
1992
Receptor tyrosine kinase substrates: src homology domains and signal transduction
Among the intracellular milieu of proteins are molecules with defined biochemical functions that serve as substrates for ligand… 
Highly Cited
1991
Highly Cited
1991
A specific type of ganglioside as a modulator of insulin-dependent cell growth and insulin receptor tyrosine kinase activity. Possible association of ganglioside-induced inhibition of insulin…
Insulin-dependent cell growth has been correlated with insulin receptor function, particularly receptor-associated kinase… 
Highly Cited
1989
Highly Cited
1989
Epidermal growth factor stimulates tyrosine phosphorylation of phospholipase C-II independently of receptor internalization and extracellular calcium.
Epidermal growth factor (EGF) rapidly stimulates the formation of inositol 1,4,5-trisphosphate in a variety of cell types… 
Highly Cited
1988
Highly Cited
1988
Suppression of nerve growth factor-directed neurite outgrowth in PC12 cells by sphingosine, an inhibitor of protein kinase C.
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