Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

Imatinib mesylate

Known as: Mesylate, Imatinib, Imatinib Methanesulfonate, Imatinib Mesylate [Chemical/Ingredient] 
The mesylate salt of imatinib, a tyrosine kinase inhibitor with antineoplastic activity. Imatinib binds to an intracellular pocket located within… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2009
Highly Cited
2009
BACKGROUND Gastrointestinal stromal tumour is the most common sarcoma of the intestinal tract. Imatinib mesylate is a small… Expand
  • table 1
  • table 2
  • table 3
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2008
Highly Cited
2008
PURPOSE The outcome of patients diagnosed with advanced gastrointestinal stromal tumor (GIST) and treated long-term with imatinib… Expand
  • table 1
  • figure 1
  • figure 2
  • table 2
  • figure 3
Is this relevant?
Highly Cited
2008
Highly Cited
2008
PURPOSE To assess potential differences in progression-free or overall survival when imatinib mesylate is administered to… Expand
  • figure 1
  • table 1
  • table 2
  • figure 2
  • figure 3
Is this relevant?
Highly Cited
2007
Highly Cited
2007
PURPOSE Response Evaluation Criteria in Solid Tumors (RECIST) are insensitive in evaluating gastrointestinal stromal tumors… Expand
  • table 1
  • table 2
  • table 3
  • figure 2
  • figure 1
Is this relevant?
Highly Cited
2006
Highly Cited
2006
Imatinib mesylate (Gleevec) is a small-molecule inhibitor of the fusion protein Bcr-Abl, the causal agent in chronic myelogenous… Expand
Is this relevant?
Highly Cited
2006
Highly Cited
2006
BACKGROUND Resistance to imatinib mesylate can occur in chronic myelogenous leukemia (CML). Preclinical in vitro studies have… Expand
  • table 1
  • figure 1
  • table 4
  • table 5
Is this relevant?
Highly Cited
2006
Highly Cited
2006
BACKGROUND No effective therapeutic options for patients with unresectable imatinib-resistant gastrointestinal stromal tumour are… Expand
Is this relevant?
Highly Cited
2003
Highly Cited
2003
PURPOSE Most gastrointestinal stromal tumors (GISTs) express constitutively activated mutant isoforms of KIT or kinase platelet… Expand
Is this relevant?
Highly Cited
2002
Highly Cited
2002
BACKGROUND Constitutive activation of KIT receptor tyrosine kinase is critical in the pathogenesis of gastrointestinal stromal… Expand
  • table 2
  • figure 1
  • figure 2
  • table 3
  • figure 3
Is this relevant?
Highly Cited
2002
Highly Cited
2002
BACKGROUND Chronic myelogenous leukemia (CML) is caused by the BCR-ABL tyrosine kinase, the product of the Philadelphia… Expand
Is this relevant?