BIBX 1382

Known as: BIBX-1382, BIBX1382 
A pyrimido-pyrimidine with antitumor activity. BIBX 1382 inhibits the intracellular tyrosine kinase domain of the Epidermal Growth Factor Receptor… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

2002-2017
012320022017

Papers overview

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2018
2018
1. Failure to predict human pharmacokinetics of aldehyde oxidase (AO) substrates using traditional allometry has been attributed… (More)
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2017
2017
Aldehyde oxidase (AO) and xanthine oxidase (XO) are molybdo-flavoenzymes that catalyze oxidation of aromatic azaheterocycles… (More)
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2015
2015
Host cell kinases are important for the replication of a number of hemorrhagic fever viruses. We tested a panel of kinase… (More)
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2015
2015
N-methyl-d-aspartate receptors (NMDARs) have been known to be regulated by various receptor tyrosine kinases. Activation of… (More)
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2014
2014
BIBX1382 was an epidermal growth factor receptor inhibitor under clinical investigation for treatment of cancer. This candidate… (More)
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2012
2012
Substrates of aldehyde oxidase (AO), for which human clinical pharmacokinetics are reported, were selected and evaluated in… (More)
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2004
2004
INTRODUCTION The model organism Caenorhabditis elegans is widely used for genetic studies as well as a living biomonitor in… (More)
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2004
2004
Overexpression of the epidermal growth factor receptors (EGFRs) and human epidermal growth factor receptor 2 occurs frequently in… (More)
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2004
2004
Exposure to ambient ultrafine particles induces airway inflammatory reactions and tissue remodeling. In this experiment, to… (More)
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2002
2002
The pyrimido-pyrimidine BIBX 1382 BS inhibits the intracellular tyrosine kinase domain of the epidermal growth factor receptor… (More)
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