EGFR gene

Known as: SPECIES ANTIGEN 7, V-ERB-B AVIAN ERYTHROBLASTIC LEUKEMIA VIRAL ONCOGENE HOMOLOG, ERBB1 
This gene is involved in the epidermal growth factor signal transduction pathway.
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
Gut homeostasis is central to whole organism health, and its disruption is associated with a broad range of pathologies… (More)
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Highly Cited
2008
Highly Cited
2008
BACKGROUND Allelic loss in chromosome 3p is one of the most frequent and earliest genetic events in lung carcinogenesis. We… (More)
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Highly Cited
2007
Highly Cited
2007
De-regulation of the wingless and integration site growth factor (WNT) signaling pathway via mutations in APC and Axin, proteins… (More)
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Highly Cited
2006
Highly Cited
2006
Increasing evidence links intraneuronal beta-amyloid (Abeta42) accumulation with the pathogenesis of Alzheimer's disease (AD). In… (More)
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Highly Cited
2005
Highly Cited
2005
BACKGROUND The antiepidermal growth factor receptor (antiEGFR) monoclonal antibodies cetuximab and panitumumab have good clinical… (More)
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Highly Cited
1992
Highly Cited
1992
This study describes genomic rearrangements near the 3' end of the epidermal growth factor receptor (EGFR) gene in eight… (More)
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Highly Cited
1992
Highly Cited
1992
Although the loss of tumor suppressor genes and the activation of oncogenes have been established as two of the fundamental… (More)
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Highly Cited
1992
Highly Cited
1992
We have until recently made several unsuccessful attempts to assign any activity to the human papillomavirus type 16 (HPV-16) E5… (More)
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Highly Cited
1988
Highly Cited
1988
Xenografts from eight malignant human gliomas were established in athymic mice and were used to study amplification and… (More)
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Highly Cited
1987
Highly Cited
1987
Primary malignant gliomas from 63 patients were analyzed to determine the relationship between amplification of the gene encoding… (More)
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