epidermal growth factor receptor VIII

Known as: EGFRvIII 
 
National Institutes of Health

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2015
2015
Glioblastoma Multiforme (GBM) is the most common and aggressive human brain tumor, associated with very poor survival despite… (More)
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2015
2015
BACKGROUND The epidermal growth factor receptor (EGFR) is a transmembrane tyrosine kinase receptor and is overexpressed in up to… (More)
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2013
2013
EGFRvIII, a mutated form of EGFR, plays a prominent role in tumorigenesis, but the underlying mechanisms have remained elusive… (More)
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Highly Cited
2013
Highly Cited
2013
EGFRvIII, a frequently occurring mutation in primary glioblastoma, results in a protein product that cannot bind ligand, but… (More)
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2012
2012
Formation of asymmetric kinase dimers is required for wt-EGFR activation upon ligand stimulation. The role of receptor… (More)
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2008
2008
Epidermal growth factor receptor (EGFR) mutation is frequently observed in human cancer and contributes to the growth, survival… (More)
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Highly Cited
2007
Highly Cited
2007
EGFRvIII is a mutant variant of the epidermal growth factor receptor (EGFR) found exclusively in various cancer types. EGFRvIII… (More)
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Highly Cited
2006
Highly Cited
2006
PURPOSE Epidermal growth factor receptor (EGFR) is overexpressed in head and neck squamous cell carcinoma (HNSCC) where… (More)
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2006
2006
PURPOSE The purpose of the present study was to evaluate a boronated EGFRvIII-specific monoclonal antibody, L8A4, for boron… (More)
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Highly Cited
1997
Highly Cited
1997
The type-III deletion variant of the epidermal growth factor receptor (EGFRvIII) is frequently found in glioblastomas and other… (More)
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