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epidermal growth factor receptor VIII

Known as: EGFRvIII 
National Institutes of Health

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2 relations
EGFR NP_005219.2:p.K29_N298insG

Broader (1)

Epidermal Growth Factor Receptor

Papers overview

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2019
2019
Rapid and ultrasensitive digital PCR (dPCR) profiling of EGFRvIII in tumor cells and tissues
Abstract Background Amplification of the epidermal growth factor receptor (EGFR) gene is commonly found in glioblastoma (GBM… 
2014
2014
NT-29UPREGULATION OF BETA-CATENIN IN PATIENT-DERIVED GLIOBLASTOMA XENOGRAFTS EXPRESSING EGFRvIII
Amplification of the EGFR gene and subsequent overexpression of EGFR is seen in about 40% of glioblastomas. Over 50% of these… 
2014
2014
Head and neck squamous cell carcinomas do not express EGFRvIII.
2014
2014
A comparative study of affibody, panitumumab, and EGF for near-infrared fluorescence imaging of EGFR- and EGFRvIII-expressing tumors
Aberrant overexpression and/or activation of epidermal growth factor receptor (EGFR) is associated with many types of cancers… 
2013
2013
Antitumor efficacy of D2C7-(scdsFv)-PE38KDEL, a novel immunotoxin targeting EGFRwt and EGFRvIII, by convection-enhanced delivery in orthotopic brain tumor mouse models
Meeting abstracts The epidermal growth factor receptor (EGFR) gene is most frequently amplified and overexpressed, along with… 
2011
2011
Nuclear Signaling of EGFR and EGFRvIII in Glioblastoma
The pivotal role of kinases in signal transduction and cellular regulation has lent them considerable appeal as therapeutic… 
Review
2010
Review
2010
Ribozyme-Mediated Inhibition of 801-bp Deletion-Mutant Epidermal Growth Factor Receptor mRNA Expression in Glioblastoma Multiforme
The epidermal growth factor receptor (HER1/EGFR) is known to be disregulated in a large subgroup of glioblastoma multiforme cases… 
Review
2010
Review
2010
Response to erlotinib in recurrent glioblastoma multiforme showing coexpression of EGFRvIII and PTEN
Glioblastoma multiforme (GBM) is the most aggressive brain tumour in adults and remains incurable despite multimodal intensive… 
2003
2003
Ribozyme Targeting the Novel Fusion Junction of EGFRvIII in Breast Cancer
Abstract : EGFRvIII is a tumor specific, ligand-independent, constitutively active variant of the epidermal growth factor… 
2001
2001
EGFR and its mutant EGFRvIII as modulators of tumor cell radiosensitivity
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