EGFR NP_005219.2:p.K29_N298insG

Known as: EGFRvIII, Epidermal Growth Factor Receptor vIII, EGFR NP_005219.2:p.V30_R297delK29_N298insG 
A deletion of 268 amino acids of the epidermal growth factor receptor protein from the valine at position 30 through the arginine at position 297… (More)

Topic mentions per year

Topic mentions per year

1995-2017
020406019952017

Papers overview

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Highly Cited
2010
Highly Cited
2010
PURPOSE Immunologic targeting of tumor-specific gene mutations may allow precise eradication of neoplastic cells without toxicity… (More)
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Highly Cited
2010
Highly Cited
2010
Human solid tumors frequently have pronounced heterogeneity of both neoplastic and normal cells on the histological, genetic, and… (More)
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Highly Cited
2008
Highly Cited
2008
Glioblastoma tumour cells release microvesicles (exosomes) containing mRNA, miRNA and angiogenic proteins. These microvesicles… (More)
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Highly Cited
2008
Highly Cited
2008
Aggressive human brain tumours (gliomas) often express a truncated and oncogenic form of the epidermal growth factor receptor… (More)
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Highly Cited
2006
Highly Cited
2006
Glioblastoma is the most common primary malignant brain tumor of adults and one of the most lethal of all cancers. Patients with… (More)
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Highly Cited
2005
Highly Cited
2005
BACKGROUND The epidermal growth factor receptor (EGFR) is frequently amplified, overexpressed, or mutated in glioblastomas, but… (More)
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Highly Cited
2005
Highly Cited
2005
BACKGROUND The epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor erlotinib (also known as Tarceva or OSI-774) has… (More)
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Highly Cited
2003
Highly Cited
2003
Glioblastoma multiforme (GBM) frequently involves amplification and alteration of the epidermal growth factor receptor (EGFR… (More)
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Highly Cited
1997
Highly Cited
1997
Deregulation of signaling by the epidermal growth factor receptor (EGFR) is common in human malignancy progression. One mutant… (More)
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Highly Cited
1995
Highly Cited
1995
Despite molecular biological advances in understanding human cancers, translation into therapy has been less forthcoming… (More)
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