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tryptophan 5-monooxygenase activity

Known as: tryptophan hydroxylase activity, tryptophan 5-hydroxylase activity, L-tryptophan,tetrahydrobiopterin:oxygen oxidoreductase (5-hydroxylating) 
Catalysis of the reaction: L-tryptophan + tetrahydrobiopterin + O2 = 5-hydroxy-L-tryptophan + 4-alpha-hydroxytetrahydrobiopterin + H2O. [EC:1.14.16.4… 
National Institutes of Health

Papers overview

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1992
1992
Increase in cortical and midbrain tryptophan hydroxylase activity by intracerebroventricular administration of corticotropin releasing factor: block by adrenalectomy, by RU 38486 and by bilateral…
Highly Cited
1991
Highly Cited
1991
Tryptophan Hydroxylase Synthesis Is Induced by 3′, 5′‐Cyclic Adenosine Monophosphate During Circadian Rhythm in the Rat Pineal Gland
: Tryptophan hydroxylase in the rat pineal gland undergoes diurnal rhythmic activity. Rat pineal glands exhibit increased… 
Highly Cited
1989
Highly Cited
1989
Increase in the activity of tryptophan hydroxylase from cortex and midbrain of male Fischer 344 rats in response to acute or repeated sound stress
Highly Cited
1985
Highly Cited
1985
Brain monoamine metabolism and behavior in portacaval-shunted rats
1983
1983
The involvement of nigral serotonin innervation in the control of punishment-induced behavioral inhibition in rats
1981
1981
Are 5-HT receptors involved in the sprouting of serotoninergic terminals following neonatal 5,7-dihydroxytryptamine treatment in the rat?
Highly Cited
1976
Highly Cited
1976
Effect of stress on serotonin concentration and tryptophan hydroxylase activity of brain nuclei.
The effects of a single stressful stimulus on serotonin (5-HT) concentration and of repeated stressful stimuli on tryptophan… 
1976
1976
EARLY RESPONSE OF RAT BRAIN TRYPTOPHAN HYDROXYLASE ACTIVITY TO CYCLOHEXIMIDE, PUROMYCIN AND CORTICOSTERONE
Abstract— The activity of tryptophan hydroxylase was measured in whole homogenates of midbrain and forebrain areas of the rat… 
Highly Cited
1972
Highly Cited
1972
Regional distribution and developmental change of tryptophan hydroxylase activity in rat brain 1
TRYPTOPHAN hydroxylase, the enzyme involved in the conversion of tryptophan to 5-hydroxytryptophan, has been detected in the… 
Highly Cited
1970
Highly Cited
1970
dl‐[2‐14C]p‐CHLOROPHENYLALANINE AS AN INHIBITOR OF TRYPTOPHAN 5‐HYDROXYLASE
The distribution in vivo of dl‐[2‐14C]p‐chlorophenylalanine (p‐CP) in regions and subcellular fractions of the rat brain was… 
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