tryptophan 5-monooxygenase activity

Known as: tryptophan hydroxylase activity, tryptophan 5-hydroxylase activity, L-tryptophan,tetrahydrobiopterin:oxygen oxidoreductase (5-hydroxylating) 
Catalysis of the reaction: L-tryptophan + tetrahydrobiopterin + O2 = 5-hydroxy-L-tryptophan + 4-alpha-hydroxytetrahydrobiopterin + H2O. [EC:1.14.16.4… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1967-2015
051019672015

Papers overview

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2007
2007
The long-term effects on marine fish populations of the recent increase worldwide in the incidence of coastal hypoxia are unknown… (More)
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1999
1999
Tryptophan hydroxylase, the initial and rate-limiting enzyme in serotonin biosynthesis, is inactivated by peroxynitrite in a… (More)
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1992
1992
Systemic administration of 3,4-methylenedioxymethamphetamine (MDMA) produces depletions of serotonin (5-HT) and its primary… (More)
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1990
1990
The role of transmitter release in the serotonergic neurotoxicity of methylenedioxymethamphetamine (MDMA) was examined using… (More)
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1989
1989
The activity of tryptophan hydroxylase (EC 1.14.16.4) from rat brain was significantly decreased 1 h following a single systemic… (More)
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Highly Cited
1987
Highly Cited
1987
The psychotomimetic agent, methylenedioxymethamphetamine, produced a rapid, persistent and dose-dependent reduction in cortical… (More)
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1987
1987
The effects of subcutaneous injection of 3,4-methylenedioxymethamphetamine (MDMA), a psychoactive amphetamine congener, on mouse… (More)
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1976
1976
In neonatal rats, administration of l-triiodothyronine (10 mug/100 g/day) for 30 days presented signs of hyperthyroidism which… (More)
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1976
1976
Selective lesions of the dorsal (B7), median (B8), or lateral (B9) raphe nuclei were made stereotaxically in male rats 4 weeks… (More)
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1969
1969
The tryptophan hydroxylase activity in the rat midbrain decreases after adrenalectomy and is restored by treatment with… (More)
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