Skip to search formSkip to main contentSkip to account menu

tryptophan 5-monooxygenase activity

Known as: tryptophan hydroxylase activity, tryptophan 5-hydroxylase activity, L-tryptophan,tetrahydrobiopterin:oxygen oxidoreductase (5-hydroxylating) 
Catalysis of the reaction: L-tryptophan + tetrahydrobiopterin + O2 = 5-hydroxy-L-tryptophan + 4-alpha-hydroxytetrahydrobiopterin + H2O. [EC:1.14.16.4… 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
Widespread endocrine disruption and reproductive impairment in an estuarine fish population exposed to seasonal hypoxia
The long-term effects on marine fish populations of the recent increase worldwide in the incidence of coastal hypoxia are unknown… 
Highly Cited
1998
Highly Cited
1998
The effects of methamphetamine on the production of free radicals and oxidative stress.
  • B. Yamamoto, W. Zhu
  • The Journal of pharmacology and experimental…
  • 1998
  • Corpus ID: 5448428
The effects of methamphetamine (METH) on pro-oxidant processes and on the production of reactive oxygen species were examined in… 
Highly Cited
1987
Highly Cited
1987
Depression of rat brain tryptophan hydroxylase activity following the acute administration of methylenedioxymethamphetamine.
Review
1986
Review
1986
The primate serotonergic system: a review of human and animal studies and a report on Macaca fascicularis.
This chapter has reviewed biochemical and morphological studies of the human and monkey serotonergic system. In addition, the… 
Highly Cited
1976
Highly Cited
1976
Histologic and enzymatic studies of the mesolimbic and mesostriatal serotonergic pathways
Highly Cited
1975
Highly Cited
1975
Long-term effects of p-chloroamphetamine and related drugs on central serotonergic mechanisms.
Earlier studies from our laboratory have demonstrated a marked reduction in the brain level of 5-hydroxytryptamine (5-HT) and in… 
Highly Cited
1974
Highly Cited
1974
Adrenalcortical influence on rat brain tryptophan hydroxylase activity.
Highly Cited
1972
Highly Cited
1972
Long-term effects of p-chloroamphetamine on tryptophan hydroxylase activity and on the levels of 5-hydroxytryptamine and 5-hydroxyindole acetic acid in brain.
Highly Cited
1971
Highly Cited
1971
Selective reduction of tryptophan hydroxylase activity in rat forebrain after midbrain raphe lesions.
Highly Cited
1969
Highly Cited
1969
Corticosterone Regulation of Tryptophan Hydroxylase in Midbrain of the Rat
The tryptophan hydroxylase activity in the rat midbrain decreases after adrenalectomy and is restored by treatment with… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy, Terms of Service, and Dataset License