• Publications
  • Influence
A description of the nicotine stimulus and tests of its generalization to amphetamine
The discriminative stimulus properties of nicotine were investigated under a variety of conditions in three separate experiments. In each of these experiments the subject's performance was assessedExpand
  • 50
  • 7
Antagonism of the effects of the hallucinogen DOM and the purported 5-HT agonist quipazine by 5-HT2 antagonists.
Rats trained to discriminate 1.0 mg/kg of 1-(2,5-dimethoxy-4-methylphenyl)-2-aminopropane (DOM) from saline in a two-lever operant choice task were administered doses of mescaline, LSD,Expand
  • 165
  • 4
Disruption of Th1/Th2 cytokine balance by cocaine is mediated by corticosterone.
Cocaine has been shown to affect immune function through the release of corticosterone. Acute administration of both cocaine and corticosterone produces an enhancement of the T-dependent antibodyExpand
  • 53
  • 4
Studies on the time course and the effect of cholinergic and adrenergic receptor blockers on the stimulus effect of nicotine
This study investigated the stimulus property of nicotine in the rat. The primary objectives of the study were 1. to determine the time course of the nicotine stimulus and its relationship to brainExpand
  • 42
  • 4
Discriminative stimulus properties of MDA analogs.
Rats trained to discriminate (+/-) 2,5-dimethoxy-4-methylphenylisopropylamine (DOM) (1.0 mg/kg) from saline, using a standard two-lever operant task, were challenged with various doses ofExpand
  • 88
  • 3
Pharmacological effects of epibatidine optical enantiomers
The pharmacology of synthetic D- and L-epibatidine, an alkaloid originally characterized from frog skin, were studied in different behavioral tests in mice and rats. The two enantiomers have potentExpand
  • 84
  • 3
DOM-stimulus generalization to LSD and other hallucinogenic indolealkylamines.
Stimulus generalization studies were conducted using rats trained to discriminate 1.0 mg/kg of the phenalkylamine hallucinogen 1-(2,5-dimethoxy-4-methylphenyl)-2-aminopropane (DOM) from saline in aExpand
  • 55
  • 3
Nicotine does not interact with the discriminative stimulus effects of clozapine in rats
The purpose of the present study was to assess the potential interaction between clozapine, an atypical antipsychotic recently approved for clinical use in the United States and nicotine. MaleExpand
  • 14
  • 3