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A Mammalian microRNA Expression Atlas Based on Small RNA Library Sequencing
Stressor specificity of central neuroendocrine responses: implications for stress-related disorders.
This review focuses mainly on the similarities and differences between the neuroendocrine responses (especially the sympathoadrenal and the sympathoneuronal systems and the hypothalamo-pituitary-adrenocortical axis) among various stressors and a strategy for testing Selye's doctrine of nonspecificity.
Isolated removal of hypothalamic or other brain nuclei of the rat.
- M. Palkovits
- BiologyBrain Research
- 14 September 1973
Physiological role of a novel neuropeptide, apelin, and its receptor in the rat brain
Results suggest that neuronal apelin plays an important role in the central control of body fluid homeostasis through its role in internalization and the pharmacological profile of the apelin receptor.
Catecholaminergic systems in stress: structural and molecular genetic approaches.
Data summarized here indicate that catecholaminergic systems are activated in different ways following exposure to distinct stressful stimuli.
Expression of Angiotensin Type-1 (AT1) and Type-2 (AT2) Receptor mRNAs in the Adult Rat Brain: A Functional Neuroanatomical Review
- Z. Lenkei, M. Palkovits, P. Corvol, C. Llorens-Cortes
- BiologyFrontiers in neuroendocrinology (Print)
- 1 October 1997
In several functional entities of the brain, such as the preoptic region, the hypothalamus, the olivocerebellary system, and the brainstem baroreflex arc, the colocalization of receptor mRNA, binding sites, and angiotensin immunoreactive nerve terminals suggests local synthesis and expression of angiotENSin II receptors.
Axonal changes in chronic demyelinated cervical spinal cord plaques.
- G. Lovas, N. Szilágyi, K. Majtényi, M. Palkovits, S. Komoly
- Biology, MedicineBrain : a journal of neurology
- 1 February 2000
The results on the cervical cord combined with other observations support the concept of slow axonal degeneration rather than acute damage as a cause of chronic disability in multiple sclerosis.
Dopamine Biosynthesis Is Selectively Abolished in Substantia Nigra/Ventral Tegmental Area but Not in Hypothalamic Neurons in Mice with Targeted Disruption of the Nurr1 Gene
Dopamine was absent in the substantia nigra and ventral tegmental area of Nurr1-null mice, consistent with absent tyrosine hydroxylase (TH), L-aromatic amino acid decarboxylase, and other DA neuron markers, providing evidence for a new mechanism of DA depletion in vivo and suggesting a unique role for Nurr 1 in fetal development and/or postnatal survival.
The LIM-homeobox gene Lhx8 is required for the development of many cholinergic neurons in the mouse forebrain
- Yangu Zhao, O. Marín, H. Westphal
- BiologyProceedings of the National Academy of Sciences…
- 10 July 2003
Genetic evidence supporting an important role for Lhx8 in development of cholinergic neurons in the forebrain is provided, as indicated by a presence of cells expressing a truncated Lx8 mRNA and mRNA of the homeobox gene Gbx1.