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tallysomycin A
National Institutes of Health
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talisomycin
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2004
2004
Monoclonal antibody mediated intracellular targeting of tallysomycin S(10b).
M. Walker
,
D. King
,
R. Dalterio
,
P. Trail
,
R. Firestone
,
G. Dubowchik
Bioorganic & Medicinal Chemistry Letters
2004
Corpus ID: 43521894
2004
2004
Tallysomycin S10b: Experimental antitumor activity and toxicity
J. Schurig
,
W. Rose
,
+4 authors
W. T. Bradner
Cancer Chemotherapy and Pharmacology
2004
Corpus ID: 21877896
SummaryTallysomycin S10b (TLM S10b), a structural analog of bleomycin (BLM), was evaluated and compared with BLM for antitumor…
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1990
1990
Phase II study of tallysomycin S10b in patients with advanced head and neck cancer
C. Nicaise
,
W. Hong
,
W. Dimery
,
J. Usakewicz
,
M. Rozencweig
,
I. Krakoff
Investigational new drugs
1990
Corpus ID: 25412343
SummaryTwenty patients with advanced head and neck tumors were entered in a phase II trial of tallysomycin S10b given…
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1990
1990
Phase II study of tallysomycin S10b in patients with advanced colorectal cancer
C. Nicaise
,
J. Ajani
,
P. Goudeau
,
M. Rozencweig
,
B. Levin
,
I. Krakoff
Cancer Chemotherapy and Pharmacology
1990
Corpus ID: 11243497
SummaryA total of 16 patients with histologically confirmed colorectal cancer were entered into this phase II trial, designed to…
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1989
1989
Substrate specificity of bleomycin hydrolase.
S. Sebti
,
J. DeLeon
,
L. Ma
,
S. Hecht
,
J. Lazo
Biochemical Pharmacology
1989
Corpus ID: 33320473
1989
1989
In vitro activity of bleomycin, tallysomycin S10b, and liblomycin against fresh human tumor cells.
E. Tueni
,
R. Newman
,
F. Baker
,
J. Ajani
,
D. Fan
,
G. Spitzer
Cancer Research
1989
Corpus ID: 2377359
The objective of this study was to compare the relative in vitro cytotoxicity of bleomycin to that of two newer-generation…
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1984
1984
The toxicological evaluation of tallysomycin s10b--biosynthetic tallysomycin derivative.
R. A. Buroker
,
C. Comereski
,
D. Barnett
,
R. Hirth
,
H. Madissoo
,
G. H. Hottendorf
Drug and chemical toxicology (New York, N.Y. )
1984
Corpus ID: 42547218
Tallysomycin S10b, a biosynthetic derivative of tallysomycin B, was subjected to intravenous toxicologic studies in mice and dogs…
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1981
1981
Tallysomycin, a new antitumor antibiotic complex related to bleomycin. V. Production, characterization and antitumor activity of tallysomycin S10b, a new biosynthetic tallysomycin derivative.
T. Miyaki
,
K. Numata
,
+5 authors
H. Kawaguchi
Journal of antibiotics (Tokyo. )
1981
Corpus ID: 23772247
Tallysomycin S10b is a biosynthetic derivative of tallysomycin B obtained by precursor amine-feeding fermentation. Tallysomycin…
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1981
1981
Tallysomycin, a new antitumor antibiotic complex related to bleomycin. IV. New biosynthetic derivatives of tallysomycin.
T. Miyaki
,
O. Tenmyo
,
+7 authors
H. Kawaguchi
Journal of antibiotics (Tokyo. )
1981
Corpus ID: 43655417
A series of new biosynthetic derivatives of tallysomycins A and B were obtained by precursor amine-feeding fermentation. Certain…
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1980
1980
Relative pulmonary toxicity and antitumor effects of two new bleomycin analogs, pepleomycin and tallysomycin A.
B. Sikic
,
Z. Siddik
,
T. E. Gram
Cancer treatment reports
1980
Corpus ID: 45635910
The relative therapeutic and toxic effects of two new analogs were compared with bleomycin over a range of doses. Therapeutic…
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