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Low molecular weight inhibitors of Myc–Max interaction and function
- Xiaoying Yin, Christine Giap, J. Lazo, E. Prochownik
- Biology, ChemistryOncogene
- 18 September 2003
TLDR
Zebrafish chemical screening reveals an inhibitor of Dusp6 that expands cardiac cell lineages
- Gabriela A Molina, A. Vogt, M. Tsang
- Biology, ChemistryNature chemical biology
- 5 July 2009
TLDR
The Substrate Recognition Domains of the N-end Rule Pathway*
- T. Tasaki, A. Zakrzewska, Drew Dudgeon, Yonghua Jiang, J. Lazo, Y. Kwon
- Biology, Computer ScienceJournal of Biological Chemistry
- 16 January 2009
TLDR
The liver X receptor ligand T0901317 decreases amyloid beta production in vitro and in a mouse model of Alzheimer's disease.
- R. Koldamova, I. Lefterov, J. Lazo
- BiologyThe Journal of biological chemistry
- 2005
TLDR
Overexpression of metallothionein confers resistance to anticancer drugs.
TLDR
microRNA-21 negatively regulates Cdc25A and cell cycle progression in colon cancer cells.
microRNAs (miRNA) are small noncoding RNAs that participate in diverse biological processes by suppressing target gene expression. Altered expression of miR-21 has been reported in cancer. To gain…
Potent and Selective Disruption of Protein Kinase D Functionality by a Benzoxoloazepinolone*
- E. Sharlow, Karthik V Giridhar, Q. J. Wang
- Biology, ChemistryJournal of Biological Chemistry
- 28 November 2008
TLDR
Chemical genetics of Plasmodium falciparum
- W. A. Guiguemde, A. Shelat, R. Guy
- Biology, MedicineNature
- 3 May 2010
TLDR
Metallothionein protects against the cytotoxic and DNA-damaging effects of nitric oxide.
- M. Schwarz, J. Lazo, J. Lancaster
- BiologyProceedings of the National Academy of Sciences…
- 9 May 1995
TLDR
Discovery and biological evaluation of a new family of potent inhibitors of the dual specificity protein phosphatase Cdc25.
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