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pyridoacridine

National Institutes of Health

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Broader (2)

AcridinesPhenanthrolines

Papers overview

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2018
2018
Naphthyridines part 4: unprecedented synthesis of polyfunctionally substituted benzo[c][2,7]naphthyridines and benzo[c]pyrimido[4,5,6-ij][2,7]naphthyridines with structural analogy to pyrido[4,3,2-mn…
An easy, efficient and one-step synthesis of the versatile, hitherto unreported of polyfunctionally substituted benzo[c][2,7… 
2014
2014
Total synthesis of the marine pyridoacridine alkaloid demethyldeoxyamphimedine.
A four-step total synthesis of the marine pyridoacridine alkaloid demethyldeoxyamphimedine (5) is presented. With an overall… 
2012
2012
A Novel Approach to the Pyridoacridine Ring System: Synthesis of the Topoisomerase Inhibitor 13‐Deazaascididemin
A novel approach to the pyridoacridine ring system of the ascididemin‐type marine alkaloids is presented. This approach allows… 
2010
2010
Evaluation of Pyridoacridine Alkaloids in a Zebrafish Phenotypic Assay
Three new minor components, the pyridoacridine alkaloids 1-hydroxy-deoxyamphimedine (1), 3-hydroxy-deoxyamphimedine (2… 
2004
2004
AK37: the first pyridoacridine described capable of stabilizing the topoisomerase I cleavable complex
Pyridoacridines are marine natural products that contain planar structures. Almost all are cytotoxic and capable of DNA… 
2004
2004
Synthesis and in vitro antitumor activity of ring C and D-substituted phenanthrolin-7-one derivatives, analogues of the marine pyridoacridine alkaloids ascididemin and meridine.
Highly Cited
2003
Highly Cited
2003
Pyridoacridine alkaloids inducing neuronal differentiation in a neuroblastoma cell line, from marine sponge Biemna fortis.
2002
2002
Three new pyridoacridine type alkaloids from a singaporean ascidian.
Two new pyridoacridine alkaloids, kuanoniamines E and F, and a new ring-opened pyridoacridine alkaloid, subarine, were isolated… 
2002
2002
Synthesis and cytotoxic evaluation of analogues of the marine pyridoacridine amphimedine.
1997
1997
Versatile Synthesis of Dihydroquinolines and Quinoline Quinones Using Cyclobutenediones. Construction of the Pyridoacridine Ring System.
1-BOC-2-lithio-1,4-dihydropyridines were condensed with 3,4-disubstituted cyclobutenediones to produce 1,2-adducts. Neat… 
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