pyridoacridine
National Institutes of Health
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A four-step total synthesis of the marine pyridoacridine alkaloid demethyldeoxyamphimedine (5) is presented. With an overall…
The extraction and purification of the bioactive extract of Cystodytes violatinctus (Solomon Islands) led to the isolation and…
Three new minor components, the pyridoacridine alkaloids 1-hydroxy-deoxyamphimedine (1), 3-hydroxy-deoxyamphimedine (2…
A new hexacyclic pyridoacridine alkaloid, nordehydrocyclodercitin (1), from an ascidian, Aplidium sp., cf. Aplidium cratiferum…
This review consolidates biological activity data reported for pyridoacridine 1 molecules in the literature from 1983-2003 into…
Pyridoacridines are marine natural products that contain planar structures. Almost all are cytotoxic and capable of DNA…
The pyridoacridine natural products represent a large and growing class and serve here to illustrate the wealth of information…
Two new pyridoacridine alkaloids, kuanoniamines E and F, and a new ring-opened pyridoacridine alkaloid, subarine, were isolated…
A new alkaloid, cycloshermilamine D, was isolated from the marine tunicate Cystodytes violatinctus, and its structure (1), which…
1-BOC-2-lithio-1,4-dihydropyridines were condensed with 3,4-disubstituted cyclobutenediones to produce 1,2-adducts. Neat…