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Acridines

Known as: Acridine, Acridines [Chemical/Ingredient] 
A polycyclic aromatic dye with antineoplastic, antimicrobial and imaging activities. Acridine and its derivatives intercalate within DNA and RNA by… 
National Institutes of Health

Related topics

Related topics

50 relations

Narrower (46)

1,3,7-trihydroxyacridone1,8-acridinedione10-methyl-9,10-dihydroacridine4-hydroxyacridine

Broader (2)

DyesHeterocyclic Compounds, 3-Ring
NCIt Antineoplastic Agent Terminologychemical synthesis

Papers overview

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1997
1997
Macrocyclic metal complexes for selective recognition of nucleic acid bases and manipulation of gene expression
Abstract 
Highly Cited
1990
Highly Cited
1990
DNA-directed alkylating agents. 1. Structure-activity relationships for acridine-linked aniline mustards: consequences of varying the reactivity of the mustard.
A series of DNA-targeted aniline mustards have been prepared, and their chemical reactivity and in vitro and in vivo cytotoxicity… 
1983
1983
Human pharmacokinetics of a new acridine derivative, 4'-(9-acridinylamino)methanesulfon-m-anisidide (NSC 249992).
The clinical pharmacology of 4'-(9-acridinylamino)methanesulfon-m-anisidide (amsacrine) was studied, utilizing [9-14C]amsacrine i… 
Highly Cited
1981
Highly Cited
1981
Potential antitumor agents. 34. Quantitative relationships between DNA binding and molecular structure for 9-anilinoacridines substituted in the anilino ring.
In an investigation of the structure-activity relationships in the 4'-(9-acridinylamino)methanesulfonanilide (AMSA) tumor… 
1977
1977
Sequence specificity of mutagen-nucleic acid complexes in solution: intercalation and mutagen-base pair overlap geometries for proflavine binding to dC-dC-dG-dG and dG-dG-dC-dC self-complementary…
The complex formed between the mutagen proflavine and the dC-dC-dG-dG and dG-dG-dC-dC self-complementary tetranucleotide duplexes… 
1976
1976
DNA polyintercalating drugs. Proton magnetic resonance studies of a new acridine dimer. Conformations and interactions with mono- and dinucleotides.
The conformation in aqueous solution of one acridine dimer which is able to bisintercalate in DNA (1, 14-bis(5-methoxy-6-chloro-9… 
1971
1971
Energy transduction in mitochondrial fragments. Interaction of the membrane with acridine dyes.
Atebrin and acridine orange fluorescence and absorbance characteristics are sensitive to their environment. Anions, such… 
Highly Cited
1971
Highly Cited
1971
Quinacrine Fluorescence in Mammalian Chromosomes
SINCE the possibilities of revealing chromosomal structure by staining chromatin with dyes derived from acridine first became… 
Highly Cited
1969
Highly Cited
1969
On the complex formation of acridine dyes with DNA. VII. Dependence of the binding on the dye structure
The binding constants for the complex formation of more than twenty ring nitrogen‐and amino‐substituted acridine derivatives with… 
1963
1963
Genetic analysis of a "double male" strain of Escherichia coli K-12.
The behavior of a double male strain of Escherichia coli K12 has been compared to that of its parents and a primary F strain…