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Acridines

Known as: Acridine, Acridines [Chemical/Ingredient] 
A polycyclic aromatic dye with antineoplastic, antimicrobial and imaging activities. Acridine and its derivatives intercalate within DNA and RNA by… 
National Institutes of Health

Related topics

Related topics

50 relations

Narrower (46)

1,3,7-trihydroxyacridone1,8-acridinedione10-methyl-9,10-dihydroacridine4-hydroxyacridine

Broader (2)

DyesHeterocyclic Compounds, 3-Ring
NCIt Antineoplastic Agent Terminologychemical synthesis

Papers overview

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1997
1997
Macrocyclic metal complexes for selective recognition of nucleic acid bases and manipulation of gene expression
Abstract 
Highly Cited
1990
Highly Cited
1990
DNA-directed alkylating agents. 1. Structure-activity relationships for acridine-linked aniline mustards: consequences of varying the reactivity of the mustard.
A series of DNA-targeted aniline mustards have been prepared, and their chemical reactivity and in vitro and in vivo cytotoxicity… 
1983
1983
Mutagenicity of diol-epoxides and tetrahydroepoxides of benz(a)acridine and benz(c)acridine in bacteria and in mammalian cells.
Abstract The mutagenic activities of benz(a)acridine, benz(c)acridine, and a number of their derivatives, including 12 epoxides… 
Highly Cited
1981
Highly Cited
1981
Potential antitumor agents. 34. Quantitative relationships between DNA binding and molecular structure for 9-anilinoacridines substituted in the anilino ring.
In an investigation of the structure-activity relationships in the 4'-(9-acridinylamino)methanesulfonanilide (AMSA) tumor… 
1977
1977
Sequence specificity of mutagen-nucleic acid complexes in solution: intercalation and mutagen-base pair overlap geometries for proflavine binding to dC-dC-dG-dG and dG-dG-dC-dC self-complementary…
The complex formed between the mutagen proflavine and the dC-dC-dG-dG and dG-dG-dC-dC self-complementary tetranucleotide duplexes… 
1976
1976
DNA polyintercalating drugs. Proton magnetic resonance studies of a new acridine dimer. Conformations and interactions with mono- and dinucleotides.
The conformation in aqueous solution of one acridine dimer which is able to bisintercalate in DNA (1, 14-bis(5-methoxy-6-chloro-9… 
Highly Cited
1974
Highly Cited
1974
AUTOMATED ANALYSIS OF DEOXYRIBONUCLEIC ACID, PROTEIN AND NUCLEAR TO CYTOPLASMIC RELATIONSHIPS IN TUMOR CELLS AND GYNECOLOGIC SPECIMENS
Quantitative two-color fluorescence staining techniques, coupled with flow system multiparameter cell analysis and sorting… 
Highly Cited
1972
Highly Cited
1972
Curing of an Escherichia coli episome by rifampicin (acridine orange-F + -F - -Hfr-lac).
Low doses of rifampicin, an antibiotic that specifically inhibits RNA polymerase, cure F(+) cells from the episome. An E. coli… 
Highly Cited
1967
Highly Cited
1967
Transposition derivatives of an Hfr strain of Escherichia coli K-12.
HE genome in Escherichia coli K-12 exists normally as one ring of doublestranded DNA (CAIRINS 1963). The fertility factor, F, is… 
1963
1963
Genetic analysis of a "double male" strain of Escherichia coli K-12.
The behavior of a double male strain of Escherichia coli K12 has been compared to that of its parents and a primary F strain…