A. Wood

Publications139
h-index51
Citations8,546
Highly Influential Citations103
Claim Author Page
Author pages are created from data sourced from our academic publisher partnerships and public sources.

Recommended Authors

  • D. Jerina
  • 622 Publications • 21,169 Citations
  • W. Levin
  • 362 Publications • 21,033 Citations
  • H. Yagi
  • 246 Publications • 8,569 Citations
  • A. Conney
  • 548 Publications • 38,746 Citations
  • Publications
  • Influence
Small-molecule antagonists of the oncogenic Tcf/beta-catenin protein complex.
Key molecular lesions in colorectal and other cancers cause beta-catenin-dependent transactivation of T cell factor (Tcf)-dependent genes. Disruption of this signal represents an opportunity for… Expand
  • 292
  • 20
Small-molecule antagonists of the oncogenic Tcf/β-catenin protein complex
Key molecular lesions in colorectal and other cancers cause beta-catenin-dependent transactivation of T cell factor (Tcf)-dependent genes. Disruption of this signal represents an opportunity for… Expand
  • 537
  • 18
  • PDF
Small molecule blockade of transcriptional coactivation of the hypoxia-inducible factor pathway.
Homeostasis under hypoxic conditions is maintained through a coordinated transcriptional response mediated by the hypoxia-inducible factor (HIF) pathway and requires coactivation by the CBP and p300… Expand
  • 413
  • 10
  • PDF
Regio- and stereoselective metabolism of two C19 steroids by five highly purified and reconstituted rat hepatic cytochrome P-450 isozymes.
High pressure liquid chromatographic systems capable of resolving at least 28 known and potential metabolites of 17 beta-hydroxy-4-androsten-3-one (testosterone) and 4-androstene-3,17-dione… Expand
  • 315
  • 5
  • PDF
Tumorigenicity of enantiomers of chrysene 1,2-dihydrodiol and of the diastereomeric bay-region chrysene 1,2-diol-3,4-epoxides on mouse skin and in newborn mice.
Abstract The tumorigenicity of chrysene, (+)- and (-)-trans-1,2-dihydroxy-1,2-dihydrochrysene (chrysene 1,2-dihydrodiol), and the (+)- and (-)-enantiomers of the diastereomeric bay-region chrysene… Expand
  • 51
  • 4
  • PDF
NMR strategy for unraveling structures of bioactive sponge-derived oxy-polyhalogenated diphenyl ethers.
The overexpression of the Mcl-1 protein in cancerous cells results in the sequestering of Bak, a key component in the regulation of normal cell apoptosis. Our investigation of the ability of… Expand
  • 39
  • 4
Mutagenesis of the Ha-ras oncogene in mouse skin tumors induced by polycyclic aromatic hydrocarbons.
The importance of mutational activation of the Ha-ras protooncogene in polycyclic aromatic hydrocarbon-induced mouse skin tumors was investigated in a complete carcinogenesis model using repetitive… Expand
  • 228
  • 3
Tumorigenicity of bay-region diol-epoxides and other benzo-ring derivatives of dibenzo(a,h)pyrene and dibenzo(a,i)pyrene on mouse skin and in newborn mice.
Abstract Dibenzo( a,h )pyrene, [DB( a,h )P], dibenzo( a,i )pyrene [DB( a,i )P], and seven of their benzo-ring derivatives were tested for tumorigenic activity on mouse skin and in newborn mice. In… Expand
  • 29
  • 3
  • PDF
Activation and inhibition of benzo(a)pyrene and aflatoxin B1 metabolism in human liver microsomes by naturally occurring flavonoids.
The effects of several naturally occurring and synthetic flavonoids on the metabolism of benzo(a)pyrene and aflatoxin B1 were evaluated. Addition of apigenin, chrysin, fisetin, flavonone, galangin,… Expand
  • 286
  • 2
  • PDF
Metabolism of benzo(a)pyrene and benzo (a)pyrene derivatives to mutagenic products by highly purified hepatic microsomal enzymes.
A highly purified and reconstituted hepatic microsomal monooxygenase system, completely free of epoxide hydrase and consisting of cytochrome P-448 from 3-methylcholanthrene-treated rats,… Expand
  • 297
  • 2
  • PDF
...
1
2
3
4
5
...