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Marine-derived fungi: a chemically and biologically diverse group of microorganisms.
A diverse array of secondary metabolites have been isolated and characterized from marine-derived fungi. The structures and biological activities of these metabolites are presented. Additionally,Expand
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WLS-dependent secretion of WNT3A requires Ser209 acylation and vacuolar acidification
Wnt proteins are secreted post-translationally modified proteins that signal locally to regulate development and proliferation. The production of bioactive Wnts requires a number of dedicated factorsExpand
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Biomedical Potential of Marine Natural Products
Marine natural products, the secondary or nonprimary metabolites produced by organisms that live in the sea, have received increasing attention from chemists and pharmacologists during the last twoExpand
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Bioactive isomalabaricane triterpenes from the marine sponge Rhabdastrella globostellata.
Two new isomalabaricane triterpenes, stellettin H (1) and stellettin I (2), have been isolated from the marine sponge Rhabdastrella globostellata, collected from the Philippines. Stellettins A-DExpand
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Distinct Pathways Generate Peptides from Defective Ribosomal Products for CD8+ T Cell Immunosurveillance
To understand better the endogenous sources of MHC class I peptide ligands, we generated an antigenic reporter protein whose degradation is rapidly and reversibly controlled with Shield-1, aExpand
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Lomaiviticins A and B, potent antitumor antibiotics from Micromonospora lomaivitiensis.
  • H. He, W. Ding, +5 authors G. Carter
  • Chemistry, Medicine
  • Journal of the American Chemical Society
  • 11 May 2001
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Anti-Parasitic Compounds from Streptomyces sp. Strains Isolated from Mediterranean Sponges
Actinomycetes are prolific producers of pharmacologically important compounds accounting for about 70% of the naturally derived antibiotics that are currently in clinical use. In this study, weExpand
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