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otonecine

Known as: oto-necine 
National Institutes of Health

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Pyrrolizidine Alkaloids

Papers overview

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2019
2019
New otonecine-type pyrrolizidine alkaloid from Petasites japonicus
One new otonecine-type pyrrolizidine alkaloid secopetasitenine (1), along with petasitenine (fukinotoxine, 2), neopetasitenine (3… 
2013
2013
Assessment of pyrrolizidine alkaloid-induced toxicity in an in vitro screening model.
2012
2012
Comparison of metabolism-mediated effects of pyrrolizidine alkaloids in a HepG2/C3A cell-S9 co-incubation system and quantification of their glutathione conjugates
Toxicity of pyrrolizidine alkaloids (PAs) largely depends on their metabolic activation by hepatic enzymes, including cytochrome… 
2007
2007
Ceroplastes albolineatus, the first scale insect shown to sequester pyrrolizidine alkaloids from its host-plant Pittocaulon praecox
Summary.The occurrence of pyrrolizidine alkaloids (PAs) in Pittocaulon (ex Senecio) praecox (Asteraceae) a species endemic to… 
Highly Cited
2006
Highly Cited
2006
Formation of DHP-derived DNA adducts from metabolic activation of the prototype heliotridine-type pyrrolizidine alkaloid, lasiocarpine.
2003
2003
Gender differences in microsomal metabolic activation of hepatotoxic clivorine in rat.
The gender differences in the in vitro microsomal metabolic activation of hepatotoxic clivorine, a representative naturally… 
2002
2002
Structure–Activity Relationships of Pyrrolizidine Alkaloids in Insect Chemical Defense Against the Orb-Weaving Spider Nephila clavipes
Pyrrolizidine alkaloids (PAs) are known to protect Arctiidae moths and Danainae and Ithomiinae butterflies against the orb… 
1989
1989
Biosynthesis of the seco-pyrrolizidine base otonecine
Putrescine homospermidine, N-(4-aminobutyl)-1,2-didehydropyrrolidinium trachelanthamidine and retronecine are all efficient… 
1988
1988
Macrocyclic pyrrolizidine alkaloids from Senecio anonymus. Separation of a complex alkaloid extract using droplet counter-current chromatography.
Ten 12-membered macrocyclic pyrrolizidine alkaloids, all of them esters of the necines, retronecine or otonecine, have been… 
1987
1987
Capillary supercritical fluid chromatography of pyrrolizidine alkaloids.
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