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- Publications
- Influence
Comprehensive Flavonol Profiling and Transcriptome Coexpression Analysis Leading to Decoding Gene–Metabolite Correlations in Arabidopsis[W][OA]
- K. Yonekura-Sakakibara, T. Tohge, +6 authors K. Saito
- Biology, Medicine
- The Plant Cell Online
- 1 August 2008
To complete the metabolic map for an entire class of compounds, it is essential to identify gene–metabolite correlations of a metabolic pathway. We used liquid chromatography–mass spectrometry… Expand
Chemistry and pharmacology of analgesic indole alkaloids from the rubiaceous plant, Mitragyna speciosa.
- H. Takayama
- Chemistry, Medicine
- Chemical & pharmaceutical bulletin
- 1 August 2004
The leaves of a tropical plant, Mitragyna speciosa KORTH (Rubiaceae), have been traditionally used as a substitute for opium. Phytochemical studies of the constituents of the plant growing in… Expand
Prenylated flavonoids and related compounds of the Indonesian Artocarpus (Moraceae)
- E. H. Hakim, Sjamsul A. Achmad, +6 authors E. Ghisalberti
- Medicine
- Journal of natural medicines
- 2006
Several species of the genus Artocarpus (Moraceae) have been investigated in our laboratories during the last decade. Over 60 phenolic constituents have been discovered and characterized, including… Expand
A New Indole Alkaloid, 7 α-Hydroxy-7H-mitragynine, from Mitragyna speciosa in Thailand
- D. Ponglux, S. Wongseripipatana, +5 authors S. Sakai
- Chemistry
- 1 December 1994
Simultaneous analysis of mitragynine, 7-hydroxymitragynine, and other alkaloids in the psychotropic plant “kratom” (Mitragyna speciosa) by LC-ESI-MS
- R. Kikura-Hanajiri, Maiko Kawamura, T. Maruyama, M. Kitajima, H. Takayama, Y. Goda
- Chemistry
- Forensic Toxicology
- 9 May 2009
The leaves of Mitragyna speciosa, a tropical plant known as “kratom,” have been traditionally used as a substitute for opium in Thailand and Malaysia. Mitragynine, a major constituent of M. speciosa,… Expand
A New Indole Alkaloid, 7 alpha-Hydroxy-7H-mitragynine, from Mitragyna speciosa in Thailand.
- D. Ponglux, S. Wongseripipatana, +5 authors S. Sakai
- Medicine
- Planta medica
- 1994
Selenosugars are key and urinary metabolites for selenium excretion within the required to low-toxic range
- Y. Kobayashi, Y. Ogra, K. Ishiwata, H. Takayama, N. Aimi, K. Suzuki
- Chemistry, Medicine
- Proceedings of the National Academy of Sciences…
- 19 November 2002
Essential micronutrient selenium is excreted into the urine and/or expired after being transformed to methylated metabolites. Monomethylated selenium is excreted into the urine in response to a… Expand
Dimethylthioarsenicals as arsenic metabolites and their chemical preparations.
- K. Suzuki, B. Mandal, +10 authors N. Aimi
- Chemistry, Medicine
- Chemical research in toxicology
- 10 June 2004
Two unidentified arsenic metabolites were detected in the liver of rats on a gel filtration column by HPLC inductively coupled argon plasma mass spectrometry after an injection of dimethylarsinic… Expand
Antinociception, tolerance and withdrawal symptoms induced by 7-hydroxymitragynine, an alkaloid from the Thai medicinal herb Mitragyna speciosa.
- K. Matsumoto, S. Horie, +5 authors K. Watanabe
- Medicine, Biology
- Life sciences
- 19 November 2005
7-Hydroxymitragynine is a potent opioid analgesic alkaloid isolated from the Thai medicinal herb Mitragyna speciosa. In the present study, we investigated the opioid receptor subtype responsible for… Expand
Antinociceptive effect of 7-hydroxymitragynine in mice: Discovery of an orally active opioid analgesic from the Thai medicinal herb Mitragyna speciosa.
- K. Matsumoto, S. Horie, +4 authors K. Watanabe
- Medicine
- Life sciences
- 12 March 2004
Mitragynine is an indole alkaloid isolated from the Thai medicinal plant Mitragyna speciosa. We previously reported the morphine-like action of mitragynine and its related compounds in the in vitro… Expand
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