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lamotrigine
Known as:
3,5-diamino-6-(2,3-dichlorophenyl)-1,2,4-triazine
, Lamotrigina
, 3,5-diamino-6-(2,3-dichlorophenyl)-as-triazine
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A synthetic phenyltriazine with antiepileptic and analgesic properties. Lamotrigine enhances the action of gamma-aminobutyric acid, an inhibitory…
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National Institutes of Health
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Related topics
Related topics
23 relations
24 HR lamotrigine 100 MG Extended Release Oral Tablet
24 HR lamotrigine 200 MG Extended Release Oral Tablet [Lamictal]
Antidepressive Agents
Antiepileptic Agents
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Broader (5)
Anticonvulsants
Calcium Channel Blockers
Excitatory Amino Acid Antagonists
Triazines
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Narrower (1)
Lamictal
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2008
Highly Cited
2008
Several major antiepileptic drugs are substrates for human P-glycoprotein
Carlos Luna-Tórtos
,
M. Fedrowitz
,
W. Löscher
Neuropharmacology
2008
Corpus ID: 1099832
Review
2007
Review
2007
Novel anticonvulsant drugs.
H. Stefan
,
T. Feuerstein
Pharmacology and Therapeutics
2007
Corpus ID: 9612708
Highly Cited
2004
Highly Cited
2004
Fracture Risk Associated with Use of Antiepileptic Drugs
P. Vestergaard
,
L. Rejnmark
,
L. Mosekilde
Epilepsia
2004
Corpus ID: 23652022
Summary: Purpose: To assess fracture risk associated with different antiepileptic drugs (AEDs). An increased fracture risk has…
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Highly Cited
2003
Highly Cited
2003
Effects of antiepileptic drugs on sleep architecture: a pilot study.
B. Legros
,
C. Bazil
Sleep Medicine
2003
Corpus ID: 22413037
Highly Cited
2002
Highly Cited
2002
Lamotrigine clearance during pregnancy
T. Tran
,
I. Leppik
,
K. Blesi
,
S. Sathanandan
,
R. Remmel
Neurology
2002
Corpus ID: 45331825
Objective To evaluate changes in lamotrigine (LTG) clearance before, during, and after pregnancy. Methods Twelve pregnancies that…
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Highly Cited
2001
Highly Cited
2001
Effectiveness of First Antiepileptic Drug
Patrick S L Kwan
,
M. Brodie
Epilepsia
2001
Corpus ID: 4426
Summary: Purpose: To investigate the interaction among efficacy, tolerability, and overall effectiveness of the first…
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Highly Cited
2000
Highly Cited
2000
A double-blind, placebo-controlled, prophylaxis study of lamotrigine in rapid-cycling bipolar disorder. Lamictal 614 Study Group.
J. R. Calabrese
,
T. Suppes
,
+8 authors
E. Monaghan
Journal of Clinical Psychiatry
2000
Corpus ID: 71423264
BACKGROUND Patients with rapid-cycling bipolar disorder are often treatment refractory. This study examined lamotrigine as…
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Highly Cited
1999
Highly Cited
1999
Risk of Stevens-Johnson syndrome and toxic epider mal necrolysis during first weeks of antiepileptic therapy: a case-control study
B. Rzany
,
O. Correia
,
J. Kelly
,
L. Naldi
,
A. Auquier
,
R. Stern
The Lancet
1999
Corpus ID: 54368499
Review
1999
Review
1999
Progress report on new antiepileptic drugs: a summary of the fourth Eilat conference (EILAT IV)
M. Bialer
,
S. Johannessen
,
H. Kupferberg
,
R. Levy
,
P. Loiseau
,
E. Perucca
Epilepsy Research
1999
Corpus ID: 21838400
Review
1998
Review
1998
Use of topiramate, a new anti-epileptic as a mood stabilizer.
David Marcotte
Journal of Affective Disorders
1998
Corpus ID: 22704802
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