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Hypoparathyroidism in the adult: Epidemiology, diagnosis, pathophysiology, target‐organ involvement, treatment, and challenges for future research
Recent advances in understanding the epidemiology, genetics, diagnosis, clinical presentations, skeletal involvement, and therapeutic approaches to hypoparathyroidism led to the First InternationalExpand
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Relative fracture risk in patients with diabetes mellitus, and the impact of insulin and oral antidiabetic medication on relative fracture risk
Aims/hypothesisWe studied the association between fractures and type 1 and type 2 diabetes mellitus.MethodsIn this case-control study, all subjects diagnosed with a fracture (n=124,655) in DenmarkExpand
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Cancellous Bone Remodeling Occurs in Specialized Compartments Lined by Cells Expressing Osteoblastic Markers
We describe a sinus, referred to as a bone remodeling compartment (BRC), which is intimately associated with cancellous bone remodeling. The compartment is lined on its marrow side by flattened cellsExpand
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Vitamin D and the elderly
This review summarizes current knowledge on vitamin D status in the elderly with special attention to definition and prevalence of vitamin D insufficiency and deficiency, relationships betweenExpand
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Increased mortality in patients with a hip fracture-effect of pre-morbid conditions and post-fracture complications
SummaryIn a cohort of 169,145 patients with a hip fracture and 524,010 controls we observed an excess mortality among patients compared to controls for as long as 20 years after the hip fracture. TheExpand
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Effect of hormone replacement therapy on cardiovascular events in recently postmenopausal women: randomised trial
Objective To investigate the long term effect of hormone replacement therapy on cardiovascular outcomes in recently postmenopausal women. Design Open label, randomised controlled trial. SettingExpand
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Diagnosis of asymptomatic primary hyperparathyroidism: proceedings of the third international workshop.
OBJECTIVE Asymptomatic primary hyperparathyroidism (PHPT) is a common clinical problem. The purpose of this report is to guide the use of diagnostic tests for this condition in clinical practice. Expand
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Efficacy and safety of recombinant human parathyroid hormone (1-84) in hypoparathyroidism (REPLACE): a double-blind, placebo-controlled, randomised, phase 3 study.
BACKGROUND Hypoparathyroidism results in impaired mineral homoeostasis, including hypocalcaemia and hyperphosphataemia. Treatment with high-dose oral calcium and active vitamin D does not provideExpand
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Proton Pump Inhibitors, Histamine H2 Receptor Antagonists, and Other Antacid Medications and the Risk of Fracture
We studied the effect of proton pump inhibitors, histamine H2 receptor antagonists, and other types of antacid drugs on fracture risk. All cases were subjects with any fracture sustained during theExpand
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Cardiovascular and renal complications to postsurgical hypoparathyroidism: A Danish nationwide controlled historic follow‐up study
We aimed to identify all patients with postsurgical hypoparathyroidism (HypoPT) and to evaluate their risks of renal complications and cardiovascular disease in relation to their disease and itsExpand
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